LACTB Recombinant Protein (OPCD04790)

Catalog No: OPCD04790

LACTB Recombinant Protein (OPCD04790) using SDS-PAGE

LACTB Recombinant Protein (OPCD04790) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Leu313-Asp547
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: LACTB
• Gene Full Name: lactamase beta
• Alias Symbols: G24;mitochondrial 39S ribosomal protein L56;MRPL56;serine beta-lactamase-like protein LACTB, mitochondrial;serine beta-lactamase-like protein, mitochondrial.
• NCBI Gene Id: 114294
• Protein Name: Serine beta-lactamase-like protein LACTB, mitochondrial
• Description of Target: Mitochondrial serine protease that acts as a regulator of mitochondrial lipid metabolism (PubMed:28329758). Acts by decreasing protein levels of PISD, a mitochondrial enzyme that converts phosphatidylserine (PtdSer) to phosphatidylethanolamine (PtdEtn), thereby affecting mitochondrial lipid metabolism (PubMed:28329758). It is unclear whether it acts directly by mediating proteolysis of PISD or by mediating proteolysis of another lipid metabolism protein (PubMed:28329758). Acts as a tumor suppressor that has the ability to inhibit proliferation of multiple types of breast cancer cells: probably by promoting decreased levels of PISD, thereby affecting mitochondrial lipid metabolism (PubMed:28329758).
• Uniprot ID: P83111
• Protein Accession #: NP_001275514.1
• Nucleotide Accession #: NM_001288585.1
• Protein Size (# AA): Leu313~Asp547
• Molecular Weight: 30kDa