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KvBeta1.2 Antibody (OASE00210)

  • Catalog#: OASE00210
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  • This product is Genway GWB-WDWDP2
100ug
$350.00
Discontinued
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Conjugation Options

OASE00210-FITC Conjugated

OASE00210-HRP Conjugated

OASE00210-Biotin Conjugated

Gene Symbol:
KCNAB1
NCBI Gene Id:
7881
Official Gene Full Name:
potassium voltage-gated channel, shaker-related subfamily, beta member 1
Swissprot Id:
Q14722
Protein Accession #:
NP_003462.
Replacement Item:
This antibody may replace item sc-11192 from Santa Cruz Biotechnology.
Host:
Mouse
Clonality:
Monoclonal
Purification:
Protein G Purified
Application:
WB, IHC, IP
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express KCNAB1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express KCNAB1.
Immunogen:
Synthetic peptide amino acids 9-28 (ADIPSPKLGLPKSSESALKC, unique N-terminus) of rat KvBeta1.2, accession number NP_003462.
Predicted Species Reactivity:
Human, Mouse, Rat
Reconstitution and Storage:
Store at -20C. Shipping in Blue Ice or 4C.
Concentration:
1mg/mL
Datasheets/Manuals:
Printable datasheet for OASE00210
Dilution:
1ug/mL (WB), 0.1-1ug/mL (IHC/ICC)
Clone:
S47-42
Isotype:
IgG1
Additional Information:
Background Info: Detects ~65kDa.
:::
Scientific Background: Depolarization-activated potassium channels (Kv) play a major role in shaping the electrical signals in the nervous system (3). KvBeta isoforms form a hetero-multimeric complex with alpha subunits and modulate the activity of the pore-forming alpha subunits (4).
:::
Certificate of Analysis: 1ug/mL was sufficient for detection of Kvbeta1.2 in 20ug of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Storage Buffer:
PBS pH7.4, 50% glycerol
Target Reference:
1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA.
2. www.iochannels.org
3. Planck-Gesellschaft M., et al. (1996) J. Physiol. 493(3): 625-633.
4. Entrez Gene “KCNAB1 potassium voltage gated channel” KCNAB1

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