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Kv4.2 Antibody (OASE00215)

  • Catalog#: OASE00215
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  • This product is Genway GWB-SO9VU8
100ug
$350.00
Discontinued
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Conjugation Options

OASE00215-FITC Conjugated

OASE00215-HRP Conjugated

OASE00215-Biotin Conjugated

Predicted Species Reactivity:
Mouse, Rat
Clonality:
Monoclonal
Clone:
S57-1
Isotype:
IgG1
Host:
Mouse
Application:
WB, IHC, IP
Additional Information:
Background Info: ~75-80kDa
:::
Scientific Background: The Kv4.2 potassium channel is a voltage-gated channel protein which belongs to the delayed rectifier class and to the ShaI potassium channel subfamily (3). All of the KV channels can product delayed-rectifier and transient “A-type” currents, all members of the KV4 subfamily mediate IA (3). Kv4 channels in the central nervous system localize to the soma and dendrites, and therefore are responsible for the somato-dendritic A-type K+ current (ISA) (3,4).
:::
Certificate of Analysis: 1ug/mL was sufficient for detection of Kv4.2 in 20ug of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Reconstitution and Storage:
Store at -20C. Shipping in Blue Ice or 4C.
Gene Symbol:
Kcnd2
NCBI Gene Id:
65180
Official Gene Full Name:
potassium voltage-gated channel, Shal-related subfamily, member 2
Swissprot Id:
Q63881
Protein Accession #:
NP_113918.2
Purification:
Protein G Purified
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express Kcnd2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express Kcnd2.
Immunogen:
Synthetic peptide amino acids 209-225 (extracellular S1-S2 loop) of rat Kv4.2 (CGSSPGHIKELPSGERY
Concentration:
1mg/mL
Datasheets/Manuals:
Printable datasheet for OASE00215
Dilution:
1ug/mL (WB), 0.1-1ug/mL (IHC/ICC), 1-10ug/mL (IF)
Storage Buffer:
PBS pH7.4, 50% glycerol
Target Reference:
1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd
Ed., Sinauer Associated Inc.: Sunderland, MA USA.
2. www.iochannels.org
3. Phuket T.R., and Covarrubias M. (2009) Front Mol Neursci.
2:3.
4. Barghaan J., and Bahring R. (2009) J Gen Physiol. 133(2):
205-224.

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