Size:100ug
$350.00
Discontinued
SKU
OASE00208-Biotin
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Conjugation Options

OASE00208 Unconjugated

OASE00208-FITC Conjugated

OASE00208-HRP Conjugated

Kv2.1 (Extracellular) Antibody : Biotin (OASE00208-Biotin)

Catalog#: OASE00208-Biotin
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Predicted Species Reactivity Human, Mouse, Rat
Product Format Liquid. Purified antibody supplied in 1x PBS buffer.
Clonality Monoclonal
Clone S39-25
Isotype IgG2a
Host Mouse
Conjugation Biotin
Application WB, ICC
Additional Information Background Info: ~105-125kDa (varies with cell background due to phosphorylation)
:: Scientific Background: Voltage gated channels are tetrameters composed of four alpha-subunits arranged around a central pore. Each alpha- subunit consists of six transmembrane segments with cytoplasmic NH2 and COHO-termini. Members of the KV1-KV4 subfamilies generate functional K+ channels in a homotetrameric configuration. The KV2 subfamily consists of KV2.1 and KV2.2, and both have very similar properties. Members of the KV2 subfamily are widely expressed in neuronal tissues. They have also been reported in neurons in the dorsal root ganglia (3-5).
:: Certificate of Analysis: 1ug/mL was sufficient for detection of Kv2.1 in 20ug of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Reconstitution and Storage All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Immunogen Synthetic peptide amino acids 11-229 (LPELQSLDEFGQSTDNPQL, extracellular S1-S2 loop) of rat Kv2.1
Purification Protein G Purified
Concentration 1 mg/ml
Datasheets/Manuals Printable datasheet for OASE00208-Biotin
Dilution 1ug/mL (WB), 0.1-1ug/mL (IHC/ICC), 1-10ug/mL (IF)
Storage Buffer PBS pH7.4, 50% glycerol
Target Reference 1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA.
2. www.iochannels.org
3. Bocksteins E., et al. (2009) Am J Physiol. 296:C1271-C1278.
4. Ishikawa K, Tanaka M, Black J.A., and Wasman S.G. (1999)
Muscle Nerve 22: 502-507.
5. Kim D.S., Choi J.O., Rim H.D., and Cho H.J. (2002) Brain Res
Mol Brain Res. 105: 146-152.
Gene Symbol Kcnb1
Official Gene Full Name potassium voltage gated channel, Shab-related subfamily, member 1
NCBI Gene Id 25736
Swissprot Id P15387
Protein Accession # NP_037318
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express Kcnb1.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express Kcnb1.
  1. What is the species homology for "Kv2.1 (Extracellular) Antibody : Biotin (OASE00208-Biotin)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".

  2. How long will it take to receive "Kv2.1 (Extracellular) Antibody : Biotin (OASE00208-Biotin)"?

    This item is available "Domestic: within 3-5 days delivery | International: 3-5 days".

  3. What buffer format is "Kv2.1 (Extracellular) Antibody : Biotin (OASE00208-Biotin)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Kv2.1 (Extracellular) Antibody : Biotin (OASE00208-Biotin)"?

    This target may also be called "" in publications.

  5. What is the shipping cost for "Kv2.1 (Extracellular) Antibody : Biotin (OASE00208-Biotin)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "Kv2.1 (Extracellular) Antibody : Biotin (OASE00208-Biotin)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Kv2.1 (Extracellular) Antibody : Biotin (OASE00208-Biotin)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Kv2.1 (Extracellular) Antibody : Biotin (OASE00208-Biotin)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "KCNB1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "KCNB1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "KCNB1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "KCNB1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "KCNB1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "KCNB1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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