Size:100ug
$350.00
Discontinued
SKU
OASE00206
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Conjugation Options

OASE00206-FITC Conjugated

OASE00206-HRP Conjugated

OASE00206-Biotin Conjugated

Kv1.1 (Extracellular) Antibody (OASE00206)

Catalog#: OASE00206
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This product is Genway GWB-EEQFU5
More Information
Predicted Species Reactivity Mouse, Rat
Clonality Monoclonal
Clone S36-15
Isotype IgG2b
Host Mouse
Application WB, ICC
Additional Information Background Info: ~56kDa (could be 65-85 depending on glycosylation)
:: Scientific Background: Kv1.1, also known as potassium voltage-gated channel subfamily A member 1, is a shaker related voltage potassium
channel that in humans is encoded by the SCNA1 gene (3-5).
It is strongly expressed in a variety of neurons in adult
rodents, and it appears to be involved in regulating neuronal
excitability. Specifically it plays a role in several
developmental processes including proliferation, migration
and cell-cell adhesion (6). The Isaacs syndrome is a result of
an autoimmune reaction against the Kv1.1 ion channel (7).
:: Certificate of Analysis: 1ug/mL was sufficient for detection of Kv1.1 in 20ug of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Reconstitution and Storage Store at -20C. Shipping in Blue Ice or 4C.
Replacement Item This antibody may replace item sc-11182 from Santa Cruz Biotechnology.
Immunogen Synthetic peptide amino acids 191-208 (ELKDDKDFTGTIHRIDNTC, extracellular domain) or rat Kv1.1
Purification Protein G Purified
Concentration 1mg/mL
Datasheets/Manuals Printable datasheet for OASE00206
Dilution 1ug/mL (WB), 0.1-1ug/mL (IHC/ICC), 1-10ug/mL (IF)
Storage Buffer PBS pH7.4, 50% glycerol
Target Reference 1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA.
2. www.iochannels.org
3. Curran M.E., Landes G.M. and Keating M.T. (1992)
Genomics. 12(4): 729-737.
4. Albrecht B., Weber K. and Pongs O. (1995) Recept.
Channels. 3(3): 213-220.
5. Gutman G.A., et al. (2005) Pharmacol Rev. 57(4): 473-
508.
6. Hallow J.L., Tempel B.L. (1998) J Neurosci. 18(15): 5682-
5691.
7. Newsom-Davis J. (1997) Ann N.Y. Acad Sci. 835: 111-119.
Gene Symbol Kcna1
Official Gene Full Name potassium voltage-gated channel, shaker-related subfamily, member 1
NCBI Gene Id 24520
Swissprot Id P10499
Protein Accession # NP_775118.1
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express Kcna1.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express Kcna1.
  1. What is the species homology for "Kv1.1 (Extracellular) Antibody (OASE00206)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Mouse, Rat".

  2. How long will it take to receive "Kv1.1 (Extracellular) Antibody (OASE00206)"?

    This item is available "Domestic: within 3-5 days delivery | International: 3-5 days".

  3. What buffer format is "Kv1.1 (Extracellular) Antibody (OASE00206)" provided in?

    This item is provided in "".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Kv1.1 (Extracellular) Antibody (OASE00206)"?

    This target may also be called "" in publications.

  5. What is the shipping cost for "Kv1.1 (Extracellular) Antibody (OASE00206)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "Kv1.1 (Extracellular) Antibody (OASE00206)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Kv1.1 (Extracellular) Antibody (OASE00206)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Kv1.1 (Extracellular) Antibody (OASE00206)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "KCNA1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "KCNA1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "KCNA1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "KCNA1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "KCNA1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "KCNA1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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