KRT5 Antibody (OAEE00379)

Catalog No: OAEE00379

Size:100UG

Western Blotting analysis of whole cell lysate of MCF-7 human breast adenocarcinoma cell line.
Lane 1: MW standard
Lane 2: immunostaining with anti-cytokeratin 5+18 (clone C-50)
Lane 3: immunostaining with Isotype mouse IgG1 control (PPV-06)

Immunohistochemistry staining of human prostate (paraffin section) using anti-cytokeratin 5+18 (clone C-50).

Product Info

• Predicted Species Reactivity: Bovine|Dog|Hamster|Human|Mouse|Porcine|Rat|Sheep
• Product Format: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Clonality: Monoclonal
• Clone: C-50
• Isotype: IgG1
• Host: Mouse
• Application: Immunocytochemistry|Immunohistochemistry-Paraffin|Immunoprecipitation|Western blot
  Positive Control: Human prostate
• Reconstitution and Storage: 2°C to 8°C
• Immunogen: Cytoskeleton preparation from HeLa cells.
• Purification: Purified
• Concentration: 1 mg/ml
• Specificity: The antibody C-50 reacts with Cytokeratin peptides 5 and 18 (58 and 45 kDa). Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues.
• Purity: > 95% (by SDS-PAGE)
• Application Info: IHC-P: 10 ug/mL
• Reference: Bartek J, Vojtesek B, Staskova Z, Bartkova J, Kerekes Z, Rejthar A, Kovarik J: A series of 14 new monoclonal antibodies to keratins: characterization and value in diagnostic histopathology. J Pathol. 1991 Jul;164(3):215-24.
  

Target Info

• Gene Symbol: KRT5
• Gene Full Name: Keratin, type II cytoskeletal 5
• Alias Symbols: K5, CK5, DDD, DDD1, EBS2, KRT5A
• NCBI Gene Id: 3852
• Protein Name: Keratin, type II cytoskeletal 5
• Description of Target: Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. Cytokeratins are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.
• Uniprot ID: P13647
• Protein Accession #: NP_000415.2
• Nucleotide Accession #: NM_000424.3