KRT15 Antibody - C-terminal region : Biotin (AVARP00005_P050-Biotin)

Catalog No: AVARP00005_P050-Biotin

Size:100ul

Product Info

• Predicted Species Reactivity: Human, Mouse, Cow
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: Biotin
• Application: IHC, WB
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human KRT15
• Predicted Homology Based on Immunogen Sequence: Cow: 86%; Human: 100%; Mouse: 86%
• Peptide Sequence: Synthetic peptide located within the following region: RSLLEGQDAKMAGIGIREASSGGGGSSSNFHINVEESVDGQVVSSHKREI
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-KRT15 (AVARP00005_P050-Biotin) antibody is Catalog # AAP30450 (Previous Catalog # AAPP34741)
• Reference: Radoja,N., et al., (2004) Mol. Cell. Biol. 24 (8), 3168-3179
• Publications:

  Celis, J. E. et al. 15-prostaglandin dehydrogenase expression alone or in combination with ACSM1 defines a subgroup of the apocrine molecular subtype of breast carcinoma. Mol. Cell. Proteomics 7, 1795-809 (2008). IHC, Bovine, Human, Mouse 18632593

Target Info

• Gene Symbol: KRT15
• Gene Full Name: Keratin 15
• Alias Symbols: K15, CK15, K1CO
• NCBI Gene Id: 3866
• Protein Name: Keratin, type I cytoskeletal 15
• Description of Target: The protein encoded by KRT15 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region on chromosome 17q21.2. The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region on chromosome 17q21.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Uniprot ID: P19012
• Protein Accession #: NP_002266
• Nucleotide Accession #: NM_002275
• Protein Size (# AA): 456
• Molecular Weight: 49kDa
• Protein Interactions: MBD3; NUP54; AMOTL2; SPG21; WAC; CYTH4; PRPF31; ARFIP2; ZFYVE26; OIP5; HMG20B; ABI2; CEP57; CREB5; HGS; USP2; LMO4; TMSB4X; SMARCE1; RAD51D; PSMB1; PSMA1; PKN1; PIK3R2; NEFL; MOS; LMO2; KRT86; KRT8; KRT6B; KRT6A; KRT5; KRT4; KIFC3; GFAP; TIMM8A; COX5B; CC