KRT15 Antibody - C-terminal region (AVARP00005_P050)

Catalog No: AVARP00005_P050

WB Suggested Anti-KRT15 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human brain

WB Suggested Anti-KRT15 antibody Titration: 1 ug/mL
Sample Type: Human HepG2

WB Suggested Anti-KRT15 antibody Titration: 1 ug/mL
Sample Type: Human Hela

WB Suggested Anti-KRT15 Antibody Titration: 4.0-8.0
Positive Control: Human Intestine

Product Info

• Publications:

  Celis, J. E. et al. 15-prostaglandin dehydrogenase expression alone or in combination with ACSM1 defines a subgroup of the apocrine molecular subtype of breast carcinoma. Mol. Cell. Proteomics 7, 1795-809 (2008). 18632593

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• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Cow
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: IHC, WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human KRT15
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 86%; Human: 100%; Mouse: 86%
• Peptide Sequence: Synthetic peptide located within the following region: RSLLEGQDAKMAGIGIREASSGGGGSSSNFHINVEESVDGQVVSSHKREI
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-KRT15 (AVARP00005_P050) antibody is Catalog # AAP30450 (Previous Catalog # AAPP34741)

Target Info

• Reference: Radoja,N., et al., (2004) Mol. Cell. Biol. 24 (8), 3168-3179
• Gene Symbol: KRT15
• Gene Full Name: Keratin 15
• Alias Symbols: K15, CK15, K1CO
• NCBI Gene Id: 3866
• Protein Name: Keratin, type I cytoskeletal 15
• Description of Target: The protein encoded by KRT15 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region on chromosome 17q21.2. The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region on chromosome 17q21.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Uniprot ID: P19012
• Protein Accession #: NP_002266
• Nucleotide Accession #: NM_002275
• Protein Size (# AA): 456
• Molecular Weight: 49kDa
• Protein Interactions: MBD3; NUP54; AMOTL2; SPG21; WAC; CYTH4; PRPF31; ARFIP2; ZFYVE26; OIP5; HMG20B; ABI2; CEP57; CREB5; HGS; USP2; LMO4; TMSB4X; SMARCE1; RAD51D; PSMB1; PSMA1; PKN1; PIK3R2; NEFL; MOS; LMO2; KRT86; KRT8; KRT6B; KRT6A; KRT5; KRT4; KIFC3; GFAP; TIMM8A; COX5B; CC