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Catalog No: OACD05038
Price: $0.00
SKU
OACD05038
Availability: Domestic: within 1-2 weeks delivery | International: within 1-2 weeks delivery
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  • $55: Antibody & Protein in US
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Datasheets/ManualsPrintable datasheet for KREMEN1 Antibody (OACD05038)
Product Info
Predicted Species ReactivityHuman|Mouse|Rat
Product FormatLiquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ApplicationImmunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot
Reconstitution and Storage2°C to 8°C|-20°C
ImmunogenRange: Lys157 - Gly390
PurificationAffinity Purified; Protein A Purified
Concentration0.5 mg/ml
Preservative0.02% NaN3
SpecificityThe antibody is a rabbit polyclonal antibody raised against KREMEN1. It has been selected for its ability to recognize KREMEN1 in immunohistochemical staining and western blotting.
FormulationPBS, pH7.4, containing 0.02% NaN3, 50% glycerol
Application DataWestern blotting: 1:50-400
Immunocytochemistry in formalin fixed cells: 1:50-500
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Immunohistochemistry in paraffin section: 1:10-100
Enzyme-linked Immunosorbent Assay: 1:100-1:5,000
Optimal working dilutions must be determined by end user.
Gene SymbolKREMEN1
Gene Full Namekringle containing transmembrane protein 1
Alias Symbolsdickkopf receptor;ECTD13;KREMEN;kremen protein 1;kringle domain-containing transmembrane protein 1;kringle-coding gene marking the eye and the nose;kringle-containing protein marking the eye and the nose;KRM1.
NCBI Gene Id83999
Protein NameKremen protein 1
Description of TargetReceptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. In the absence of DKK1, potentiates Wnt-beta-catenin signaling by maintaining LRP5 or LRP6 at the cell membrane. Can trigger apoptosis in a Wnt-independent manner and this apoptotic activity is inhibited upon binding of the ligand DKK1. Plays a role in limb development; attenuates Wnt signaling in the developing limb to allow normal limb patterning and can also negatively regulate bone formation. Modulates cell fate decisions in the developing cochlea with an inhibitory role in hair cell fate specification.
Uniprot IDQ96MU8
Protein Accession #NP_001034659.2
Nucleotide Accession #NM_001039570
Molecular Weight50 kDa
  1. What is the species homology for "KREMEN1 Antibody (OACD05038)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".

  2. How long will it take to receive "KREMEN1 Antibody (OACD05038)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: within 1-2 weeks delivery".

  3. What buffer format is "KREMEN1 Antibody (OACD05038)" provided in?

    This item is provided in "Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "KREMEN1 Antibody (OACD05038)"?

    This target may also be called "dickkopf receptor;ECTD13;KREMEN;kremen protein 1;kringle domain-containing transmembrane protein 1;kringle-coding gene marking the eye and the nose;kringle-containing protein marking the eye and the nose;KRM1." in publications.

  5. What is the shipping cost for "KREMEN1 Antibody (OACD05038)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "KREMEN1 Antibody (OACD05038)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "KREMEN1 Antibody (OACD05038)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "50 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "KREMEN1 Antibody (OACD05038)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "KREMEN1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "KREMEN1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "KREMEN1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "KREMEN1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "KREMEN1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "KREMEN1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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