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- $55: Antibody & Protein in US
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Datasheets/Manuals | Printable datasheet for KREMEN1 Antibody - C-terminal (OAPB01726) (OAPB01726) |
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Predicted Species Reactivity | Human|Mouse|Rat |
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Product Format | Liquid. KREMEN1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Clonality | Polyclonal |
Isotype | IgG |
Host | Rabbit |
Conjugation | Unconjugated |
Application | Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot |
Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Immunogen | Rabbit polyclonal KREMEN1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human KREMEN1. The immunogen is located within the last 50 amino acids of KREMEN1. |
Purification | Affinity Purified |
Concentration | 1 mg/ml |
Gene Symbol | KREMEN1 |
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Gene Full Name | kringle containing transmembrane protein 1 |
Alias Symbols | dickkopf receptor;ECTD13;KREMEN;kremen protein 1;kringle domain-containing transmembrane protein 1;kringle-coding gene marking the eye and the nose;kringle-containing protein marking the eye and the nose;KRM1. |
NCBI Gene Id | 83999 |
Protein Name | Kremen protein 1|kremen protein 1 isoform 2 precursor [Homo sapiens] |
Description of Target | Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. In the absence of DKK1, potentiates Wnt-beta-catenin signaling by maintaining LRP5 or LRP6 at the cell membrane. Can trigger apoptosis in a Wnt-independent manner and this apoptotic activity is inhibited upon binding of the ligand DKK1. Plays a role in limb development; attenuates Wnt signaling in the developing limb to allow normal limb patterning and can also negatively regulate bone formation. Modulates cell fate decisions in the developing cochlea with an inhibitory role in hair cell fate specification. |
Uniprot ID | Q96MU8 |
Protein Accession # | https://www.ncbi.nlm.nih.gov/protein/NP_114434 |
Nucleotide Accession # | NM_001039570.2 |
Molecular Weight | 54 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "KREMEN1 Antibody - C-terminal (OAPB01726)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".
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How long will it take to receive "KREMEN1 Antibody - C-terminal (OAPB01726)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "KREMEN1 Antibody - C-terminal (OAPB01726)" provided in?
This item is provided in "Liquid. KREMEN1 Antibody is supplied in PBS containing 0.02% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "KREMEN1 Antibody - C-terminal (OAPB01726)"?
This target may also be called "dickkopf receptor;ECTD13;KREMEN;kremen protein 1;kringle domain-containing transmembrane protein 1;kringle-coding gene marking the eye and the nose;kringle-containing protein marking the eye and the nose;KRM1." in publications.
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What is the shipping cost for "KREMEN1 Antibody - C-terminal (OAPB01726)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "KREMEN1 Antibody - C-terminal (OAPB01726)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "KREMEN1 Antibody - C-terminal (OAPB01726)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "54 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "KREMEN1 Antibody - C-terminal (OAPB01726)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "KREMEN1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "KREMEN1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "KREMEN1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "KREMEN1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "KREMEN1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "KREMEN1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.