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Catalog No: OPCD04725
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OPCD04725
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Datasheets/ManualsPrintable datasheet for KRAS Recombinant Protein (OPCD04725)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Met1-Met189
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity>95%
SourceE.coli
TagN-terminal His Tag
Gene SymbolKRAS
Gene Full NameKRAS proto-oncogene, GTPase
Alias Symbolscellular c-Ki-ras2 proto-oncogene;cellular transforming proto-oncogene;CFC2;c-Ki-ras;c-Ki-ras2;c-Kirsten-ras protein;C-K-RAS;'C-K-RAS;GTPase KRas;KI-RAS;Kirsten rat sarcoma viral oncogene homolog;Kirsten rat sarcoma viral proto-oncogene;K-Ras;K-Ras 2;K-ras p21 protein;KRAS1;KRAS2;K-RAS2A;K-RAS2B;K-RAS4A;K-RAS4B;NS;NS3;OES;oncogene KRAS2;PR310 c-K-ras oncogene;RALD;RASK2;transforming protein p21;v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog.
NCBI Gene Id3845
Protein NameGTPase KRas
Description of TargetRas proteins bind GDP/GTP and possess intrinsic GTPase activity (PubMed:20949621). Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838). Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner (PubMed:24623306).
Uniprot IDP01116
Protein Accession #NP_004976.2
Nucleotide Accession #NM_004985.4
Protein Size (# AA)Met1~Met189
Molecular Weight25kDa
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