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KRAS Antibody - FITC Conjugated (OACA01930)
| Datasheets/Manuals | Printable datasheet for KRAS Antibody - FITC Conjugated (OACA01930) (OACA01930) |
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| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Liquid |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | FITC |
| Application | WB |
| Reconstitution and Storage | -20°C or -80°C |
| Immunogen | Recombinant Human GTPase KRas protein (2-168AA) |
| Purification | Protein G Purified |
| Concentration | Varies by lot. See vial for exact concentration. |
| Purity | > 95% |
| Reference | [1] Structure and organization of the human Ki-ras proto-oncogene and a related processed pseudogene.'McGrath J.P., Capon D.J., Smith D.H., Chen E.Y., Seeburg P.H., Goeddel D.V., Levinson A.D.Nature 304:501-506(1983) [2] Structure of the Ki-ras gene of the human lung carcinoma cell line Calu-1.'Shimizu K., Birnbaum D., Ruley M.A., Fasano O., Suard Y., Edlund L., Taparowsky E., Goldfarb M., Wigler M.Nature 304:497-500(1983) [3] Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations.'Capon D.J., Seeburg P.H., McGrath J.P., Hayflick J.S., Edman U., Levinson A.D., Goeddel D.V.Nature 304:507-513(1983) |
| Publications | Phenotypic Switching of Naïve T Cells to Immune-Suppressive Treg-Like Cells by Mutant KRAS. J Clin Med. 8, (2019). 31635338 |
| Description |
| Gene Symbol | KRAS |
|---|---|
| Gene Full Name | KRAS proto-oncogene, GTPase |
| Alias Symbols | cellular c-Ki-ras2 proto-oncogene, cellular transforming proto-oncogene, CFC2, c-Ki-ras, c-Ki-ras2, c-Kirsten-ras protein, C-K-RAS, C-K-RAS, GTPase KRas, KI-RAS, Kirsten rat sarcoma viral oncogene homolog, Kirsten rat sarcoma viral proto-oncogene, K-Ras |
| NCBI Gene Id | 3845 |
| Protein Name | GTPase KRas |
| Description of Target | Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (PubMed:20949621). Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838). Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner (PubMed:24623306). |
| Uniprot ID | P01116 |
| Protein Accession # | NP_004976.2; NP_203524.1; XP_006719132.1 |
| Nucleotide Accession # | NM_004985.4; NM_033360.3; XM_006719069.2 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "KRAS Antibody - FITC Conjugated (OACA01930)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "KRAS Antibody - FITC Conjugated (OACA01930)"?
This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".
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What buffer format is "KRAS Antibody - FITC Conjugated (OACA01930)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "KRAS Antibody - FITC Conjugated (OACA01930)"?
This target may also be called "cellular c-Ki-ras2 proto-oncogene, cellular transforming proto-oncogene, CFC2, c-Ki-ras, c-Ki-ras2, c-Kirsten-ras protein, C-K-RAS, C-K-RAS, GTPase KRas, KI-RAS, Kirsten rat sarcoma viral oncogene homolog, Kirsten rat sarcoma viral proto-oncogene, K-Ras" in publications.
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What is the shipping cost for "KRAS Antibody - FITC Conjugated (OACA01930)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "KRAS Antibody - FITC Conjugated (OACA01930)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "KRAS Antibody - FITC Conjugated (OACA01930)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "KRAS Antibody - FITC Conjugated (OACA01930)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "KRAS"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "KRAS"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "KRAS"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "KRAS"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "KRAS"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "KRAS"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
