Catalog No: ARP54671_P050
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ARP54671_P050
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KPNA1 Antibody - N-terminal region (ARP54671_P050)

Datasheets/ManualsPrintable datasheet for anti-KPNA1 (ARP54671_P050) antibody
Product Info
ReferenceTheodore,M., (2008) J. Biol. Chem. 283 (14), 8984-8994
Tested Species ReactivityHuman, Mouse
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human KPNA1
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 77%; Zebrafish: 85%
Peptide SequenceSynthetic peptide located within the following region: NMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVIS
Concentration0.5 mg/ml
Blocking PeptideFor anti-KPNA1 (ARP54671_P050) antibody is Catalog # AAP54671 (Previous Catalog # AAPP31462)
Subunitalpha-1
Gene SymbolKPNA1
Gene Full NameKaryopherin alpha 1 (importin alpha 5)
Alias SymbolsRCH2, SRP1, IPOA5, NPI-1
NCBI Gene Id3836
Protein NameImportin subunit alpha-1
Description of TargetRecombination activating proteins RAG1 and RAG2 regulate and mediate V(D)J recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. KPNA1 interacts with RAG1 and may play a role in V(D)J recombination.Recombination activating proteins RAG1 and RAG2 regulate and mediate V(D)J recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. The protein encoded by this gene interacts with RAG1 and may play a role in V(D)J recombination. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Uniprot IDP52294
Protein Accession #NP_002255
Nucleotide Accession #NM_002264
Protein Size (# AA)538
Molecular Weight60kDa
Protein InteractionsUBC; TAF9; CLK4; NUP50; ANP32B; XRN2; rev; TRMT61A; KCTD12; NPM1; GABPA; DCAF6; LIMCH1; HECW2; CLK3; HDAC2; HDAC1; GOPC; HDAC6; CRADD; LMO4; BCAR3; FOSL1; SKP2; ORC4; IL1RAP; AICDA; TP53BP1; KPNB1; RAG1; NOSIP; DCAF8; ANP32A; CAND1; COPS5; CUL1; CUL3; CUL
  1. What is the species homology for "KPNA1 Antibody - N-terminal region (ARP54671_P050)"?

    The tested species reactivity for this item is "Human, Mouse". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish".

  2. How long will it take to receive "KPNA1 Antibody - N-terminal region (ARP54671_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "KPNA1 Antibody - N-terminal region (ARP54671_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "KPNA1 Antibody - N-terminal region (ARP54671_P050)"?

    This target may also be called "RCH2, SRP1, IPOA5, NPI-1" in publications.

  5. What is the shipping cost for "KPNA1 Antibody - N-terminal region (ARP54671_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "KPNA1 Antibody - N-terminal region (ARP54671_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "KPNA1 Antibody - N-terminal region (ARP54671_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "60kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "KPNA1 Antibody - N-terminal region (ARP54671_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "KPNA1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "KPNA1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "KPNA1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "KPNA1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "KPNA1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "KPNA1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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