KMT5C Recombinant Protein (OPCD07255)

Catalog No: OPCD07255

Product Info

• Predicted Species Reactivity: Mouse|Mus musculus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Gly2-Leu279
  Subcellular Location: Nucleus. Chromosome
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Kmt5c
• Gene Full Name: lysine methyltransferase 5C
• Alias Symbols: [histone H4]-lysine20 N-methyltransferase KMT5B;[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B;BC024816;histone-lysine N-methyltransferase KMT5C;histone-lysine N-methyltransferase SUV420H2;lysine-specific methyltransferase 5C;su(var)4-20 homolog 2;suppressor of variegation 4-20 homolog 2;Suv420;Suv4-20;Suv420h2;Suv4-20h2.
• NCBI Gene Id: 232811
• Protein Name: Histone-lysine N-methyltransferase KMT5C
• Description of Target: Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5C is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2).
• Uniprot ID: Q6Q783
• Protein Accession #: NP_001108490.1
• Nucleotide Accession #: NM_001115018.1
• Protein Size (# AA): Gly2~Leu279
• Molecular Weight: 33kDa