Catalog No: OAGA02393
Size:100 ul
Price: $372.00
SKU
OAGA02393
Availability: Domestic: within 1-2 week delivery | International: 1-2 weeks
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for anti-KLRK1 (OAGA02393) antibody
Product Info
Predicted Species ReactivityHuman
Product FormatLiquid. 1XPBS, 40% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ApplicationICC, IF, IHC-P, WB
Reconstitution and StorageKeep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
ImmunogenCarrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human NKG2D. The exact sequence is proprietary.
PurificationPurified by antigen-affinity chromatography.
Concentration1mg/ml
Application InfoSuggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000 [suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)]. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Gene SymbolKLRK1
Gene Full Namekiller cell lectin-like receptor subfamily K, member 1
Alias SymbolsKLR, CD314, NKG2D, NKG2-D, D12S2489E
NCBI Gene Id22914
Description of TargetNatural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. This gene encodes a member of the NKG2 family. The encoded transmembrane protein is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain. It binds to a diverse family of ligands that include MHC class I chain-related A and B proteins and UL-16 binding proteins, where ligand-receptor interactions can result in the activation of NK and T cells. The surface expression of these ligands is important for the recognition of stressed cells by the immune system, and thus this protein and its ligands are therapeutic targets for the treatment of immune diseases and cancers. Read-through transcription exists between this gene and the upstream KLRC4 (killer cell lectin-like receptor subfamily C, member 4) family member in the same cluster.
Uniprot IDP26718
  1. What is the species homology for "KLRK1 Antibody - middle region (OAGA02393)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "KLRK1 Antibody - middle region (OAGA02393)"?

    This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".

  3. What buffer format is "KLRK1 Antibody - middle region (OAGA02393)" provided in?

    This item is provided in "Liquid. 1XPBS, 40% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "KLRK1 Antibody - middle region (OAGA02393)"?

    This target may also be called "KLR, CD314, NKG2D, NKG2-D, D12S2489E" in publications.

  5. What is the shipping cost for "KLRK1 Antibody - middle region (OAGA02393)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "KLRK1 Antibody - middle region (OAGA02393)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "KLRK1 Antibody - middle region (OAGA02393)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "KLRK1 Antibody - middle region (OAGA02393)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "KLRK1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "KLRK1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "KLRK1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "KLRK1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "KLRK1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "KLRK1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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