KLF4 Recombinant Protein (OPCD04684)

Catalog No: OPCD04684

KLF4 Recombinant Protein (OPCD04684) using SDS-PAGE

KLF4 Recombinant Protein (OPCD04684) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Mouse|Mus musculus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Ser240-His478
  Subcellular Location: Nucleus
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Klf4
• Gene Full Name: Kruppel-like factor 4 (gut)
• Alias Symbols: epithelial zinc finger protein EZF;EZF;Gkl;Gklf;gut-enriched krueppel-like factor;Krueppel-like factor 4;Kruppel-like factor 4 (Gut enriched kruppel-like factor) (Epithelial zinc-finger protein EZF);kruppel-like factor 4 isoform Klf4-108;kruppel-like factor 4 isoform Klf4-1355;kruppel-like factor 4 isoform Klf4-1482;kruppel-like factor 4 isoform Klf4-178;kruppel-like factor 4 isoform Klf4-343;kruppel-like factor 4 isoform Klf4-375;kruppel-like factor 4 isoform Klf4-51;kruppel-like factor 4 isoform Klf4-550;kruppel-like factor 4 isoform Klf4-725;Zi;Zie.
• NCBI Gene Id: 16600
• Protein Name: Krueppel-like factor 4
• Description of Target: Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription (By similarity).
• Uniprot ID: Q60793
• Protein Accession #: NP_034767.2
• Nucleotide Accession #: NM_010637.3
• Protein Size (# AA): Ser240~His478
• Molecular Weight: 33kDa