Size:100 ul
$319.00
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SKU
ARP32760_P050
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Conjugation Options

ARP32760_P050-FITC Conjugated

ARP32760_P050-HRP Conjugated

ARP32760_P050-Biotin Conjugated

More Information
Tested Species Reactivity Human
Predicted Species Reactivity Guinea Pig, Human, Mouse, Pig, Rat, Zebrafish
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application CHIP, IHC, WB
Additional Information IHC Information: Brain, cerebellum
IHC Information: Colon, myenteric plexus
IHC Information: Lung
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-18690 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human KLF2
Purification Affinity Purified
Predicted Homology Based on Immunogen Sequence Guinea Pig: 93%; Human: 100%; Mouse: 93%; Pig: 100%; Rat: 93%; Zebrafish: 79%
Complete computational species homology data Anti-KLF2 (ARP32760_P050)
Peptide Sequence Synthetic peptide located within the following region: PPAFGLFDDAAAAAAALGLAPPAARGLLTPPASPLELLEAKPKRGRRSWP
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-KLF2 (ARP32760_P050) antibody is Catalog # AAP32760 (Previous Catalog # AAPP03775)
Datasheets/Manuals Printable datasheet for anti-KLF2 (ARP32760_P050) antibody
Target Reference Saavedra,M.T., (2008) Am. J. Respir. Cell Mol. Biol. 38 (6), 679-688
Publications

Yamada, T., Park, C. S., Mamonkin, M. & Lacorazza, H. D. Transcription factor ELF4 controls the proliferation and homing of CD8+ T cells via the Krüppel-like factors KLF4 and KLF2. Nat. Immunol. 10, 618-26 (2009). CHIP, IHC, WB, Guinea Pig, Human, Mouse, Pig, Rat, Zebrafish 19412182

Gene Symbol KLF2
Official Gene Full Name Kruppel-like factor 2 (lung)
Alias Symbols LKLF
NCBI Gene Id 10365
Protein Name Krueppel-like factor 2
Description of Target KLF2 belongs to the krueppel C2H2-type zinc-finger protein family. It contains 3 C2H2-type zinc fingers. KLF2 binds to the CACCC box in the beta-globin gene promoter and activates transcription.
Swissprot Id Q9Y5W3
Protein Accession # NP_057354
Nucleotide Accession # NM_016270
Protein Size (# AA) 355
Molecular Weight 37kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express KLF2.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express KLF2.
Protein Interactions KAT2B; EP300; CREBBP; FBXW7; UBC; GSK3B; ELAVL1; SMURF1; WWP1; GATA5; GATA6; WEE1;
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