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Datasheets/Manuals | Printable datasheet for KLF11 Antibody (OAAF02396) |
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Predicted Species Reactivity | Human|Mouse|Rat |
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Product Format | Liquid |
Clonality | Polyclonal |
Host | Rabbit |
Application | Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin |
Reconstitution and Storage | -20°C |
Immunogen | The antiserum was produced against synthesized peptide derived from human KLF10/11. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Specificity | KLF10/11 antibody detects endogenous levels of total KLF10/11 protein. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Dilution | The optimal working dilution should be determined by the end user. |
Application Info | IHC: 1:50~1:100; ELISA: 1:5000 |
Reference | Subramaniam M., Nucleic Acids Res. 23:4907-4912(1995). Fautsch M.P., Genomics 51:408-416(1998). Johnsen S.A., J. Biol. Chem. 277:30754-30759(2002). |
Gene Symbol | KLF10|KLF11 |
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Gene Full Name | Kruppel like factor 10|Kruppel like factor 11 |
Alias Symbols | early growth response-alpha;EGRA;EGR-alpha;FKLF;FKLF1;Krueppel-like factor 10;Krueppel-like factor 11;MODY7;TGFB-inducible early growth response protein 1;TGFB-inducible early growth response protein 2;TIEG;TIEG1;TIEG2;TIEG-2;Tieg3;transforming growth factor-beta-inducible early growth response protein 1;transforming growth factor-beta-inducible early growth response protein 2;zinc finger transcription factor TIEG. |
NCBI Gene Id | 7071|8462 |
Protein Name | Krueppel-like factor 10|Krueppel-like factor 11 |
Description of Target | Transcription factor (PubMed:9748269, PubMed:10207080). Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth (PubMed:9748269, PubMed:10207080, PubMed:16131492). Represses transcription of SMAD7 which enhances TGF-beta signaling (By similarity). Induces apoptosis (By similarity).|Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Plays a role in the regulation of the circadian clock; binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity. Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis (By similarity). May play a role in the cell cycle regulation. |
Uniprot ID | O14901|Q13118 |
Protein Accession # | NP_001171187.1 |
Molecular Weight | 52 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "KLF11 Antibody (OAAF02396)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".
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How long will it take to receive "KLF11 Antibody (OAAF02396)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "KLF11 Antibody (OAAF02396)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "KLF11 Antibody (OAAF02396)"?
This target may also be called "early growth response-alpha;EGRA;EGR-alpha;FKLF;FKLF1;Krueppel-like factor 10;Krueppel-like factor 11;MODY7;TGFB-inducible early growth response protein 1;TGFB-inducible early growth response protein 2;TIEG;TIEG1;TIEG2;TIEG-2;Tieg3;transforming growth factor-beta-inducible early growth response protein 1;transforming growth factor-beta-inducible early growth response protein 2;zinc finger transcription factor TIEG." in publications.
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What is the shipping cost for "KLF11 Antibody (OAAF02396)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "KLF11 Antibody (OAAF02396)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "KLF11 Antibody (OAAF02396)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "52 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "KLF11 Antibody (OAAF02396)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "KLF10|KLF11"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "KLF10|KLF11"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "KLF10|KLF11"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "KLF10|KLF11"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "KLF10|KLF11"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "KLF10|KLF11"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.