Catalog No: OPCD04677
Price: $0.00
SKU
OPCD04677
Availability: Domestic: within 1-2 weeks delivery | International: within 1-2 weeks delivery
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Datasheets/Manuals | Printable datasheet for KISS1 Recombinant Protein (OPCD04677) |
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Predicted Species Reactivity | Mouse|Mus musculus |
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Product Format | Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose. |
Host | E.coli |
Conjugation | Unconjugated |
Application | Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot |
Additional Information | Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method) |
:: | Residues: Met1-Gly126 |
:: | Subcellular Location: Secreted |
Reconstitution and Storage | 2°C to 8°C|-80°C |
Concentration | 200 ug/mL (prior to lyoph) |
Purity | > 90% |
Source | E.coli |
Tag | N-terminal His and GST Tag |
Gene Symbol | Kiss1 |
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Gene Full Name | KiSS-1 metastasis-suppressor |
Alias Symbols | 0610012C01Rik;kis;Kiss1 metastasis-suppressor;kisspeptin;kisspeptin-1;meta;metastasis-suppressor KiSS-1;metastatin;metastin. |
NCBI Gene Id | 280287 |
Protein Name | Metastasis-suppressor KiSS-1 |
Description of Target | Metastasis suppressor protein. May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. Intracerebroventricular administration induces an increase in serum LH and FSH levels in prepubertal male and female as well as in adult animals. |
Uniprot ID | Q6Y4S4 |
Protein Accession # | NP_839991.2 |
Nucleotide Accession # | NM_178260.3 |
Protein Size (# AA) | Met1~Gly126 |
Molecular Weight | 44kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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