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- $55: Antibody & Protein in US
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Datasheets/Manuals | Printable datasheet for anti-KIR2DS4 (OAAN00528) |
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Predicted Species Reactivity | Human |
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Product Format | Liquid |
Clonality | Polyclonal |
Isotype | IgG |
Host | Rabbit |
Conjugation | Unconjugated |
Application | WB, IHC |
Reconstitution and Storage | Store at -20C. Avoid repeated freeze/thaw cycles. |
Immunogen | Recombinant protein of human KIR2DS4 |
Purification | Affinity purified against immunogen |
Preservative | 0.02% Sodium Azide |
Application Info | WB: 1:500 - 1:2,000. IHC: 1:50 - 1:200 |
Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Gene Symbol | KIR2DS4 |
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Gene Full Name | killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4 |
Alias Symbols | KKA3, KIR1D, NKAT8, CD158I, KIR412, NKAT-8, KIR-2DS4 |
NCBI Gene Id | 3809 |
Protein Name | Killer cell immunoglobulin-like receptor 2DS4 |
Description of Target | Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. |
Uniprot ID | P43632 |
Protein Accession # | NP_001268900.1 |
Nucleotide Accession # | NM_001281971.1 |
Molecular Weight | 34 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "KIR2DS4 Antibody (OAAN00528)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "KIR2DS4 Antibody (OAAN00528)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "KIR2DS4 Antibody (OAAN00528)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "KIR2DS4 Antibody (OAAN00528)"?
This target may also be called "KKA3, KIR1D, NKAT8, CD158I, KIR412, NKAT-8, KIR-2DS4" in publications.
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What is the shipping cost for "KIR2DS4 Antibody (OAAN00528)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "KIR2DS4 Antibody (OAAN00528)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "KIR2DS4 Antibody (OAAN00528)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "34 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "KIR2DS4 Antibody (OAAN00528)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "KIR2DS4"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "KIR2DS4"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "KIR2DS4"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "KIR2DS4"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "KIR2DS4"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "KIR2DS4"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.