KIR2DL3 Antibody (OASA01323)

Catalog No: OASA01323 (Formerly GWB-6A6D2C)

Size:200UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. Phosphate buffered saline
• Clonality: Monoclonal
• Clone: GL183
• Isotype: IgG1
• Host: Mouse
• Application: Flow cytometry|Immunoprecipitation
• Additional Information: Fusion Partners: Spleen cells from immunised BALB/c mice were fused with cells of the mouse P3UI myeloma cell line.
  Preservative Stabilisers: 0.09% Sodium Azide (NaN₃)
  0.5% Bovine Serum Albumin
  Approx Protein Conc: IgG concentration 1.0 mg/ml
  Buffer Solutions: Phosphate buffered saline
• Reconstitution and Storage: -20°C
• Immunogen: NK cell clone E57 (Moretta et al. 1985).
• Predicted Homology Based on Immunogen Sequence: Human
• Concentration: 1 mg/ml
• Specificity: CD158b
• Application Info: Flow Cytometry:    1/10 - 1/50
  
• Reference: 1. Moretta, A. et al. (1990) A novel surface antigen expressed by a subset of human CD3-CD16+ natural killer cells. J. Exp. Med. 171: 695 - 714.
  2. Moretta, A. et al. (1993) p58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class-I protected cells in NK clones displaying different specificities. J. Exp. Med. 178: 597-604.
  3. Ciccone, E. et al. (1992) Evidence of a natural killer (NK) cell repertoire for (allo) antigen recognition: definition of five distinct NK-determined allospecificities in humans. J. Exp. Med. 175: 709-718.
  4. Moretta, A. et al. (1997) Major histocompatibility complex class I - specific receptors on human natural killer and T lymphocytes. Immunol Rev. 155: 105-117.
  5. Moretta, A. et al. (1995) Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells. J. Exp. Med. 182: 875-884.
  6. Biassoni, R. et al. (1996) The human leukocyte antigen (HLA)-C-specific "activatory" or "inhibitory" natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions. J. Exp. Med. 183: 645-650.
  7. Long, E.O. et al. (1996) Inhibitory MHC Class I receptors on NK and T cells: a standard nomenclature. Immunol. Today 17: 100.
  

Target Info

• Gene Symbol: KIR2DL3
• Alias Symbols: p58, NKAT, GL183, NKAT2, CD158b, KIR2DL, NKAT2A, NKAT2B, CD158B2, KIR-K7b, KIR-K7c, KIR2DS5, KIRCL23, KIR-023GB
• NCBI Gene Id: 3804
• Protein Name: Killer cell immunoglobulin-like receptor 2DL3
• Description of Target: MOUSE ANTI HUMAN CD158b
  
• Uniprot ID: P43628
• Protein Accession #: NP_056952.2
• Protein Size (# AA): 341