KIF3B Antibody - C-terminal region (ARP33908_P050)

Size:100 ul

Human HepG2

Basic Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Replacement Item: This antibody may replace item sc-136208 from Santa Cruz Biotechnology.
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human KIF3B
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 92%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 100%
• Complete computational species homology data: Anti-KIF3B (ARP33908_P050)
• Peptide Sequence: Synthetic peptide located within the following region: APKVQAALDAALQDEDEIQVDASSFESTANKKSKARPKSGRKSGSSSSSS
• Concentration: Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
• Blocking Peptide: For anti-PARP1 (ARP33908_P050) antibody is Catalog # AAP33908 (Previous Catalog # AAPP04979)
• Datasheets/Manuals: Printable datasheet for anti-PARP1 (ARP33908_P050) antibody
• Target Reference: Jimbo,T., et al., (2002) Nat. Cell Biol. 4 (4), 323-327
• Publications:

  Weisschuh, N., Alavi, M. V, Bonin, M. & Wissinger, B. Identification of genes that are linked with optineurin expression using a combined RNAi-microarray approach. Exp. Eye Res. 85, 450-61 (2007). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 17663987

Target Info

• Gene Symbol: PARP1
• Official Gene Full Name: Poly (ADP-ribose) polymerase 1
• Alias Symbols: PARP, PPOL, ADPRT, ADPRT1, PARP-1, ADPRT 1, pADPRT-1, KIF3B
• NCBI Gene Id: 142
• Protein Name: Kinesin-like protein KIF3B
• Description of Target: The protein encoded by the KIF3B gene acts as a heterodimer with kinesin family member 3A to aid in chromosome movement during mitosis and meiosis. The encoded protein is a plus end-directed microtubule motor and can interact with the SMC3 subunit of the cohesin complex. In addition, the encoded protein may be involved in the intracellular movement of membranous organelles. This protein and kinesin family member 3A form the kinesin II subfamily of the kinesin superfamily.
• Swissprot Id: O15066
• Protein Accession #: NP_004789
• Nucleotide Accession #: NM_004798
• Protein Size (# AA): 747
• Molecular Weight: 85kDa
• Tissue Tool: Find tissues and cell lines supported by DNA array analysis to express KIF3B.
• RNA Seq: Find tissues and cell lines supported by RNA-seq analysis to express KIF3B.
• Protein Interactions: PARP1; CASP7; CASP3; UBE2I; TP53; SUMO2; CHFR; BANP; HUWE1; MDM2; SUMO3; DNMT1; CHD1L; IVNS1ABP; DDB2; PARP9; UBC; Rnf146; APLF; UHRF1; RPA3; RPA2; RPA1; ERG; MAFF; POLG2; RPL35; RPL27A; RPL19; RAD23A; PHB; CETN2; CETN1; DDX39A; PDLIM7; RPL14; MAFK; MAFG;