KIF1A Antibody - N-terminal region (ARP33900_P050)

Catalog No: ARP33900_P050

25 ug of the indicated Human whole cell extracts was loaded onto a 6-18% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. The protein may be modified by phosphorylation.

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KIF1A
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 79%; Rat: 100%; Yeast: 100%; Zebrafish: 79%
• Peptide Sequence: Synthetic peptide located within the following region: TTIVNPKQPKETPKSFSFDYSYWSHTSPEDINYASQKQVYRDIGEEMLQH
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-KIF1A (ARP33900_P050) antibody is Catalog # AAP33900 (Previous Catalog # AAPP04971)
• Reference: Kikkawa,M. (2006) EMBO J. 25 (18), 4187-4194

Target Info

• Gene Symbol: KIF1A
• Gene Full Name: Kinesin family member 1A
• Alias Symbols: ATSV, MRD9, HSN2C, SPG30, UNC104, C2orf20, NESCAVS
• NCBI Gene Id: 547
• Protein Name: Kinesin-like protein KIF1A
• Description of Target: KIF1A is the motor for anterograde axonal transport of synaptic vesicle precursors.The protein encoded by this gene is a member of the kinesin family. This protein is highly similar to mouse heavy chain kinesin member 1A protein which is an anterograde motor protein that transports membranous organelles along axonal microtubules. It is thought that this protein may play a critical role in the development of axonal neuropathies resulting from impaired axonal transport. There are multiple polyadenylation sites found in this gene. Sequence Note: X90840.1 is a chimeric sequence. Only the ATSV region was propagated into this RefSeq record. [6/26/03, RefSeq staff]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Uniprot ID: Q12756
• Protein Accession #: NP_004312
• Nucleotide Accession #: NM_004321
• Protein Size (# AA): 1690
• Molecular Weight: 191kDa
• Protein Interactions: RFX6; RNF31; ADAMTSL4; TENC1; MTUS2; MID2; RBPMS; SPRY2; FXR2; BZRAP1; RGS20; MKRN3; TRIP6; TRAF1; TRIM27; PSMA3; PLSCR1; MDFI; AR; NOTCH2NL; SP1; Dlg4; UBC; SIRT7; RXRA; MED1; PPARG; ESR1; GIT1; KIF1A; UL56;