Size:100 ul
$289.00
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ARP72851_P050-FITC
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Conjugation Options

ARP72851_P050 Unconjugated

ARP72851_P050-HRP Conjugated

ARP72851_P050-Biotin Conjugated

KDM5B Antibody - C-terminal region : FITC (ARP72851_P050-FITC)

Catalog#: ARP72851_P050-FITC
Domestic: within 1-2 days delivery | International: 1-2 days
Click here to learn more about Aviva's By-Request Conjugation Service.
More Information
Predicted Species Reactivity Human
Product Format Liquid. Purified antibody supplied in 1x PBS buffer.
Clonality Polyclonal
Host Rabbit
Conjugation FITC (FAM): Excitation 495 nm/ Emission 520 nm
Application WB
Reconstitution and Storage All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Immunogen The immunogen is a synthetic peptide directed towards the C-terminal region of Human KDM5B
Purification Affinity Purified
Peptide Sequence Synthetic peptide located within the following region: EMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQ
Concentration 0.5 mg/ml
Blocking Peptide For anti-KDM5B (ARP72851_P050-FITC) antibody is Catalog # AAP72851
Datasheets/Manuals Printable datasheet for anti-KDM5B (ARP72851_P050-FITC) antibody
Gene Symbol KDM5B
Alias Symbols KDM5B, JARID1B, PLU1, RBBP2H1,
NCBI Gene Id 10765
Description of Target KDM5B is a histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. It does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. KDM5B demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. It acts as a transcriptional corepressor for FOXG1B and PAX9. It favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, KDM5B may act as a tumor suppressor for melanoma.
Swissprot Id Q9UGL1
Protein Accession # NP_006609
Protein Size (# AA) 1544
Molecular Weight 169kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express KDM5B.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express KDM5B.
Protein Interactions FBXW11; UBC; HDAC2; HDAC4; SUMO1; SUMO3; PPP1CA; TFAP2C; MYC; HDAC7; HDAC5; NCOR1; PAX9; HDAC1; ELAVL1; CHD3; MTA3; MBD3; KDM1A; MTA2; MBD2; RBBP7; RBBP4; RB1; SUMO2; KLF10; LMO2; FOXG1; AR; VGLL3; PRDM13; ARID1B; BMP2K; RNF43; RBM15B; DBNL; CECR6; SLC39A
  1. What is the species homology for "KDM5B Antibody - C-terminal region : FITC (ARP72851_P050-FITC)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "KDM5B Antibody - C-terminal region : FITC (ARP72851_P050-FITC)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "KDM5B Antibody - C-terminal region : FITC (ARP72851_P050-FITC)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "KDM5B Antibody - C-terminal region : FITC (ARP72851_P050-FITC)"?

    This target may also be called "KDM5B, JARID1B, PLU1, RBBP2H1, " in publications.

  5. What is the shipping cost for "KDM5B Antibody - C-terminal region : FITC (ARP72851_P050-FITC)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "KDM5B Antibody - C-terminal region : FITC (ARP72851_P050-FITC)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "KDM5B Antibody - C-terminal region : FITC (ARP72851_P050-FITC)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "169kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "KDM5B Antibody - C-terminal region : FITC (ARP72851_P050-FITC)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "KDM5B"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "KDM5B"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "KDM5B"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "KDM5B"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "KDM5B"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "KDM5B"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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