KDM4C Recombinant Protein (OPCD04648)

Catalog No: OPCD04648

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Leu685-Lys871
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: KDM4C
• Gene Full Name: lysine demethylase 4C
• Alias Symbols: [histone H3]-trimethyl-L-lysine(9) demethylase 4C;GASC1;gene amplified in squamous cell carcinoma 1 protein;JHDM3C;JmjC domain-containing histone demethylation protein 3C;JMJD2C;jumonji domain-containing protein 2C;lysine (K)-specific demethylase 4C;lysine-specific demethylase 4C;TDRD14C;tudor domain containing 14C.
• NCBI Gene Id: 23081
• Protein Name: Lysine-specific demethylase 4C
• Description of Target: Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.
• Uniprot ID: Q9H3R0
• Protein Accession #: NP_001140167.1
• Nucleotide Accession #: NM_001146695.1
• Protein Size (# AA): Leu685~Lys871
• Molecular Weight: 22kDa