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KCTD10 Antibody - C-terminal region (OAAB09706)

400ul
$390.00
In Stock
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Gene Symbol:
KCTD10
NCBI Gene Id:
83892
Protein Name:
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3
Swissprot Id:
Q9H3F6
Protein Accession #:
NP_114160.1
Alias Symbols:
KCTD10, ULR061, BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3, BTB/POZ domain-containing protein KCTD10, Potassium channel tetramerization domain-containing protein 10
Replacement Item:
This antibody may replace item sc-109303, HPA014273
Description of Target:
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Molecular Weight:
35432 Da
Host:
Rabbit
Clonality:
Polyclonal
Application:
WB, IHC, FC
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express KCTD10.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express KCTD10.
Immunogen:
This KCTD10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-301 amino acids from the C-terminal region of human KCTD10.
Predicted Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Human
Product Format:
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Reconstitution and Storage:
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Approximately 0.5mg/ml. Actual concentration varies with each lot.
Datasheets/Manuals:
Printable datasheet for OAAB09706
Isotype:
Ig
Application Info:
WB: 1:1000
IHC-P: 1:10~50
FC: 1:10~50
Additional Information:
Precautions: KCTD10 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
:::
Function: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex. The BCR(BACURD3) E3 ubiquitin ligase complex mediates the ubiquitination of target proteins, leading to their degradation by the proteasome (By similarity)
:::
Cellular Location: Nucleus.
Publications:

Wang, Y. et al. KCTD10 interacts with proliferating cell nuclear antigen and its down-regulation could inhibit cell proliferation. J. Cell. Biochem. 106, 409-13 (2009). WB, IHC, FC, Human 19125419

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