KCNN2 Antibody (Asp244) (OASG04059)

Catalog No: OASG04059

Size:100 uL

Western Blot

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid. PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IHC
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthetic Peptide
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.
• Concentration: 1 mg/ml
• Application Info: WB 1:500~2000
  IHC 1:100~300
  

Target Info

• Gene Symbol: KCNN2
• Gene Full Name: potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
• Alias Symbols: SK2, hSK2, SKCA2, KCa2.2, SKCa 2
• NCBI Gene Id: 3781;
• Description of Target: Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene is a member of the KCNN family of potassium channel genes. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Alternate splicing of this gene results in multiple transcript variants.
• Uniprot ID: Q6PJI0