KCNJ11 Antibody - N-terminal region (OAAB05801)

Catalog No: OAAB05801

Size:400UL

Western blot analysis of KCNJ11 Antibody (N-term) in mouse stomach tissue lysates (35ug/lane). KCNJ11 (arrow) was detected using the purified Pab.

KCNJ11 Antibody (N-term) flow cytometry analysis of CEM cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rabbit
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Host: Rabbit
• Application: FC,WB
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This KCNJ11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human KCNJ11.
• Predicted Homology Based on Immunogen Sequence: Human; Mouse
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Application Info: WB: 1:1000
  FC: 1:10~50
• Other Applications Image 1 Data: KCNJ11 Antibody (N-term) flow cytometry analysis of CEM cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Target Info

• Gene Symbol: KCNJ11
• Alias Symbols: ATP-sensitive inward rectifier potassium channel 11, ATP-sensitive inward rectifier potassium channel Kir6.2, beta-cell inward rectifier subunit, BIR, HHF2, IKATP, inward rectifier K(+) channel Kir6.2, inwardly rectifing potassium channel subfamily J member 11, inwardly rectifying potassium channel KIR6.2, inwardly-rectifying potassium channel subfamily J member 11, Kir6, KIR6.2, mBIR, MODY13, PHHI, PNDM2, potassium channel inwardly rectifing subfamily J member 11, potassium channel, inwardly rectifying subfamily J member 11, potassium voltage-gated channel subfamily J member 11, TNDM3.
• NCBI Gene Id: 100008648|16514|3767
• Protein Name: ATP-sensitive inward rectifier potassium channel 11|ATP-sensitive inward rectifier potassium channel 11 isoform 2 [Homo sapiens]
• Description of Target: This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium (By similarity). Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation.|This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium. Can form cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation (By similarity).
• Uniprot ID: O02822|Q14654|Q61743
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_001159762.1
• Molecular Weight: 43526