KCNJ1 Antibody (Phospho-Ser44) (OASG06461)

Catalog No: OASG06461

Size:100 uL

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: IHC, IF
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from human ROM-K around the phosphorylation site of S44. Location: 30-110aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Target Post-Translational Modification: Phospho-Ser44
• Specificity: Phospho-ROM-K (S44) Polyclonal Antibody detects endogenous levels of ROM-K protein only when phosphorylated at S44.
• Application Info: IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000;

Target Info

• Gene Symbol: KCNJ1
• Gene Full Name: potassium channel, inwardly rectifying subfamily J, member 1
• Alias Symbols: ROMK, ROMK1, KIR1.1
• NCBI Gene Id: 3758; 56379; 24521
• Description of Target: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.
• Uniprot ID: P48048, O88335, P35560
• Molecular Weight: 45 kDa