KCND3 Antibody - C-terminal region (ARP36727_P050)

Catalog No: ARP36727_P050

Host: Rabbit
Target Name: KCND3
Sample Tissue: Liver Tumor lysates
Antibody Dilution: 1ug/ml

Host: Mouse
Target Name: KCND3
Sample Tissue: Mouse Spleen
Antibody Dilution: 1ug/ml

Product Info

• Tested Species Reactivity: Human, Mouse
• Predicted Species Reactivity: Human
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KCND3
• Purification: Affinity purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
• Peptide Sequence: Synthetic peptide located within the following region: GLRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGPNTNIPSIASNV
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-KCND3 (ARP36727_P050) antibody is Catalog # AAP36727

Target Info

• Gene Symbol: KCND3
• Gene Full Name: potassium voltage-gated channel subfamily D member 3
• Alias Symbols: KV4.3, SCA19, SCA22, BRGDA9, KCND3L, KCND3S, KSHIVB
• NCBI Gene Id: 3752
• Protein Name: potassium voltage-gated channel subfamily D member 3
• Description of Target: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene.
• Uniprot ID: Q9UK17
• Protein Accession #: NP_004971.2
• Nucleotide Accession #: NM_004980.4
• Protein Size (# AA): 655
• Molecular Weight: 72 kDa
• Protein Interactions: NDUFS2; NAP1L1; LBR; HSPA8; HSPA5; HNRNPF; XRCC6; EWSR1; EMD; DDB1; CUX1; CDK1; AUP1; NONO; XRCC5; UQCRC2; TUBB2A; RCN2; Rapgef5; Rapgef4; Kcnip1; Rapgef3; Kcnip2; DPP10; PYCR2; VPS4A; TUBA1B; G3BP1; RUVBL1; CNBP; SRC; KCND3;