Kappa light chain Antibody (OAAB06904)

Catalog No: OAAB06904

Size:400ul

Kappa light chain Antibody western blot analysis in human serum protein (35ug/lane).This demonstrates the Kappa light chain antibody detected the Kappa light chain protein (arrow).

Kappa light chain Antibody (Cat. #OAAB06904)immunohistochemistry analysis in formalin fixed and paraffin embedded human lymph tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Kappa light chain Antibody for immunohistochemistry. Clinical relevance has not been evaluated.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. PBS with 0.09% (W/V) sodium azide
• Clonality: Monoclonal
• Clone: HP6053
• Isotype: IgG1,k
• Host: Mouse
• Application: WB, IHC-P
• Additional Information: Cellular Location: Secreted. Cell membrane
  
• Reconstitution and Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This Kappa light chain monoclonal antibody is generated from mouse immunized with Kappa light chain recombinant protein.
• Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.
• Concentration: 0.5 mg/ml
• Application Info: WB: 1:100~1000
  IHC-P: 1:10~50
  Optimal dilutions should be determined by the end user.
• Intended Use: For research use only and not for use in diagnostic or therapeutic procedures.
• Reference: 58066: Reimer CB, et al. Evaluation of thirty-one mouse monoclonal antibodies to human IgG epitopes. Hybridoma 3: 263-275, 1984. PubMed: 6209201

Target Info

• Gene Symbol: IGKC
• Alias Symbols: IGKC, Ig kappa chain C region
• Protein Name: Ig kappa chain C region
• Description of Target: Immunoglobulins recognize foreign antigens and initiate immune responses such as phagocytosis and the complement system. Each immunoglobulin molecule consists of two identical heavy chains and two identical light chains. There are two types of light chains designated as kappa and lambda. Light chain types are based on differences in the amino acid sequence in the constant region of the light chain. If a cell is unsuccessful in rearranging both of its kappa light chain genes, it then attempts to make a lambda light chain. If a cell successfully rearranges a lambda light chain gene, it will be a B cell that makes an immunoglobulin with a lambda light chain.
• Uniprot ID: P01834
• Molecular Weight: 12 kDa