K8 Antibody (OAEC04254)

Catalog No: OAEC04254

Size:100 ug/100 ul

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Immunohistochemical analysis of paraffin-embedded human lymphnode, showing membrane localization using CD14 mouse mAb with DAB staining.

Flow cytometric analysis of human PBMC using CD14 mouse mAb.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Purified antibody in PBS containing 0.03% sodium azide
• Clonality: Monoclonal
• Clone: 5A3
• Isotype: IgG1
• Host: Mouse
• Application: IHC, IF
• Reconstitution and Storage: Store at 4C, for long term storage, store at -20C.
• Immunogen: Purified recombinant fragment of human CD14 expres sed in EColi.
• Concentration: 1 mg/ml
• Application Info: IHC: 1/200 - 1/1000
  IF: 1/200 - 1/1000
  ELISA: 1/10000
  Figure 1 Immunohistochemical analysis of paraffin-embedded human lym phnode
  showing membrane localization using CD14 mouse mAbwith DAB staining
  

Target Info

• Gene Symbol: K8
• Gene Full Name: bZIP transcription factor
• NCBI Gene Id: 4961462
• Description of Target: CD14 antigen is a GPI-linked glycoprotein with a molecular weight of 55kD. The CD14 antigen is expres sed on cells of the myelomonocytic lineage including monocytes , macrophages and Langerhans cells. Low expression is observed on neutrophils and on human B cells. CD14 antigen is a receptor for bacterial lipopolys accharide (LPS, endotoxin) and the lipopolys accharide binding protein (LBP). LBP and CD14 antigen serves two phys iological roles. These proteins act as opsonin and opsonic receptor, respectively, to promote the phagocytic uptake of bacteria or LPScoated particles by macrophages.
• Uniprot ID: Q2HR82