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JMJD3 Antibody - N-terminal region (ARP40101_P050)

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100 ul
$319.00
In Stock
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Conjugation Options

ARP40101_P050-FITC Conjugated

ARP40101_P050-HRP Conjugated

ARP40101_P050-Biotin Conjugated

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Gene Symbol:
KDM6B
Official Gene Full Name:
Lysine (K)-specific demethylase 6B
NCBI Gene Id:
23135
Protein Name:
Lysine-specific demethylase 6B
Swissprot Id:
O15054
Protein Accession #:
NP_001073893
Nucleotide Accession #:
NM_001080424
Alias Symbols:
KIAA0346, JMJD3
Description of Target:
JMJD3 is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It plays a central role in regulation of posterior development, by regulating HOX gene expression. It is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.
Protein Size (# AA):
1682
Molecular Weight:
181kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express JMJD3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express JMJD3.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human JMJD3
Predicted Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Tested Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%
Complete computational species homology data:
Anti-JMJD3 (ARP40101_P050)
Peptide Sequence:
Synthetic peptide located within the following region: HRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASI
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
WDR5; ASH2L; RBBP5; UBC; TK1; CSNK2B; HIST1H3A; WAS; SMAD3; SMAD2; SMAD4; SMAD1;
Blocking Peptide:
For anti-KDM6B (ARP40101_P050) antibody is Catalog # AAP40101 (Previous Catalog # AAPP22939)
Datasheets/Manuals:
Printable datasheet for anti-KDM6B (ARP40101_P050) antibody
Target Reference:
Hong,S., (2007) Proc. Natl. Acad. Sci. U.S.A. 104 (47), 18439-18444

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