- Tested Species Reactivity:
- Human
- Predicted Species Reactivity:
- Human
- Product Format:
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
- Clonality:
- Polyclonal
- Host:
- Rabbit
- Application:
- WB
- Reconstitution and Storage:
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
- Immunogen:
- The immunogen is a synthetic peptide directed towards the C terminal region of human JMJD2D
- Purification:
- Protein A purified
- Predicted Homology Based on Immunogen Sequence:
- Human: 100%
- Complete computational species homology data:
- Anti-JMJD2D (ARP35946_T100)
- Peptide Sequence:
- Synthetic peptide located within the following region: SSTPGPSAQIIHPSNGRRGRGRPPQKLRAQELTLQTPAKRPLLAGTTCTA
- Concentration:
- Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
- Blocking Peptide:
- For anti-KDM4D (ARP35946_T100) antibody is Catalog # AAP35946 (Previous Catalog # AAPP07204)
- Datasheets/Manuals:
- Printable datasheet for anti-KDM4D (ARP35946_T100) antibody
- Target Reference:
- Katoh,M. et al., (2004) Int. J. Oncol. 24 (6), 1623-1628
- Publications:
Kim, T.-D. et al. Pro-growth role of the JMJD2C histone demethylase in HCT-116 colon cancer cells and identification of curcuminoids as JMJD2 inhibitors. Am. J. Transl. Res. 6, 236-47 (2014). WB, Human 24936217
Kim, T.-D., Oh, S., Shin, S. & Janknecht, R. Regulation of tumor suppressor p53 and HCT116 cell physiology by histone demethylase JMJD2D/KDM4D. PLoS One 7, e34618 (2012). WB, Human 22514644
- Gene Symbol:
- KDM4D
- Official Gene Full Name:
- Lysine (K)-specific demethylase 4D
- Alias Symbols:
- JMJD2D
- NCBI Gene Id:
- 55693
- Protein Name:
- Lysine-specific demethylase 4D
- Description of Target:
- JMJD2D belongs to JMJD2 family that is consist of four cancer-associated genes
- Swissprot Id:
- Q6B0I6
- Protein Accession #:
- NP_060509
- Nucleotide Accession #:
- NM_018039
- Protein Size (# AA):
- 523
- Molecular Weight:
- 59kDa
- Tissue Tool:
- Find tissues and cell lines supported by DNA array analysis to express JMJD2D.
- RNA Seq:
- Find tissues and cell lines supported by RNA-seq analysis to express JMJD2D.
- Protein Interactions:
- HECW2; PPP1CC; CUL4B; TP53; AR; KDM4D;
Product Reviews
- Protocol:
- Tips Information:
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