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JMJD2D antibody - C-terminal region (ARP35946_T100)

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100 ul
$229.00
In Stock
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Conjugation Options

ARP35946_T100-FITC Conjugated

ARP35946_T100-HRP Conjugated

ARP35946_T100-Biotin Conjugated

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Gene Symbol:
KDM4D
NCBI Gene Id:
55693
Official Gene Full Name:
Lysine (K)-specific demethylase 4D
Protein Name:
Lysine-specific demethylase 4D
Swissprot Id:
Q6B0I6
Protein Accession #:
NP_060509
Nucleotide Accession #:
NM_018039
Alias Symbols:
JMJD2D
Description of Target:
JMJD2D belongs to JMJD2 family that is consist of four cancer-associated genes
Protein Size (# AA):
523
Molecular Weight:
59kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Protein A purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express JMJD2D.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express JMJD2D.
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human JMJD2D
Tested Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Human: 100%
Complete computational species homology data:
Anti-JMJD2D (ARP35946_T100)
Peptide Sequence:
Synthetic peptide located within the following region: SSTPGPSAQIIHPSNGRRGRGRPPQKLRAQELTLQTPAKRPLLAGTTCTA
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
HECW2; PPP1CC; CUL4B; TP53; AR; KDM4D;
Blocking Peptide:
For anti-KDM4D (ARP35946_T100) antibody is Catalog # AAP35946 (Previous Catalog # AAPP07204)
Datasheets/Manuals:
Printable datasheet for anti-KDM4D (ARP35946_T100) antibody
Target Reference:
Katoh,M. et al., (2004) Int. J. Oncol. 24 (6), 1623-1628
Publications:

Kim, T.-D., Oh, S., Shin, S. & Janknecht, R. Regulation of tumor suppressor p53 and HCT116 cell physiology by histone demethylase JMJD2D/KDM4D. PLoS One 7, e34618 (2012). WB, Human 22514644

Kim, T.-D. et al. Pro-growth role of the JMJD2C histone demethylase in HCT-116 colon cancer cells and identification of curcuminoids as JMJD2 inhibitors. Am. J. Transl. Res. 6, 236-47 (2014). WB, Human 24936217

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