JMJD1C Antibody (OAPB00950)

Catalog No: OAPB00950

Size:100UG

Western blot analysis of JMJD1C in human liver tissue lysate with JMJD1C antibody at (A) 1 and (B) 2 ug/mL.

Immunohistochemistry of JMJD1C in rat liver tissue with JMJD1C antibody at 2.5 ug/mL.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid. JMJD1C Antibody is supplied in PBS containing 0.02% sodium azide.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
  Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
• Reconstitution and Storage: JMJD1C antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Immunogen: JMJD1C antibody was raised against a 20 amino acid synthetic peptide from near the amino terminus of human JMJD1C. The immunogen is located within amino acids 380 - 430 of JMJD1C.
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human; Mouse; Rat
• Concentration: 1 mg/ml
• Blocking Peptide: For anti-JMJD1C antibody is Catalog # OEPB03067
• Application Info: JMJD1C antibody can be used for detection of JMJD1C by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
• Reference: Katoh M and Katoh M. Identification of TRIP8 gene in silico. Int. J. Mol. Med.2003; 12:817-21.;Castermans D, Vermeesch JR, Fryns JP, et al. Identification and characterization of the TRIP8 and REEP3 genes on chromosome 10q21.3 as novel candidate genes for autism. Eur. J. Hum. Genet.2007; 15:422-31.;Katoh M and Katoh M. Comparative integromics on JMJD1C gene encoding histone demethylase: Conserved POU5F1 binding site elucidating mechanism of JMJD1C expression in undifferentiated ES cells and diffuse-type gastric cancer. Int. J. Oncology2007; 31:219-23.;Katoh Y and Katoh M. Conserved POU-binding site linked to SP1-binding site within FZD5 promoter: transcriptional mechanism of FZD5 in undifferentiated human ES cells, fetal liver/spleen, adult colon, pancreatic islet, and diffuse-type gastric cancer. Int. J. Oncol.2007; 30:751-5.

Target Info

• Gene Symbol: JMJD1C
• Gene Full Name: jumonji domain containing 1C
• Alias Symbols: Jumonji domain-containing protein 1C;KDM3C;probable JmjC domain-containing histone demethylation protein 2C;thyroid hormone receptor interactor 8;thyroid receptor-interacting protein 8;TR-interacting protein 8;TRIP8;TRIP-8.
• NCBI Gene Id: 221037
• Protein Name: Probable JmjC domain-containing histone demethylation protein 2C|probable JmjC domain-containing histone demethylation protein 2C isoform a [Homo sapiens]
• Description of Target: Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes (By similarity).
• Uniprot ID: Q15652
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_116165