Size:100 ul
$359.00
In Stock
SKU
OABF00123
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Conjugation Options

OABF00123-FITC Conjugated

OABF00123-HRP Conjugated

OABF00123-Biotin Conjugated

ITGB3 Antibody (OABF00123)

Catalog#: OABF00123
Domestic: within 1 week delivery | International: 1 week
More Information
Predicted Species Reactivity Human, Mouse
Product Format Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.
Clonality Polyclonal
Isotype IgG
Host Rabbit
Conjugation Unconjugated
Application WB, FC, IHC-P, ICC
Additional Information Subcellular location: Extracellular
Reconstitution and Storage Store at -20C for 12 months.
Replacement Item This antibody may replace item sc-13579 from Santa Cruz Biotechnology.
Immunogen KLH conjugated synthetic peptide derived from human Integrin beta 3
Purification Purified by Protein A.
Concentration 1ug/ul
Datasheets/Manuals Printable datasheet for OABF00123
Application Info WB: 1:100 - 1000
ELISA: 1:500 - 1000
FC: 1:20 - 100
IHC-P: : 1:100 - 500
Gene Symbol ITGB3
Official Gene Full Name integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
Alias Symbols GT, CD61, GP3A, BDPLT2, GPIIIa, BDPLT16,
NCBI Gene Id 3690
Description of Target Integrin alpha-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. Fibrinogen binding enhances SELP expression in activated platelets (By similarity). In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Swissprot Id P05106
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express ITGB3.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express ITGB3.
  1. What is the species homology for "ITGB3 Antibody (OABF00123)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse".

  2. How long will it take to receive "ITGB3 Antibody (OABF00123)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "ITGB3 Antibody (OABF00123)" provided in?

    This item is provided in "Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ITGB3 Antibody (OABF00123)"?

    This target may also be called "GT, CD61, GP3A, BDPLT2, GPIIIa, BDPLT16, " in publications.

  5. What is the shipping cost for "ITGB3 Antibody (OABF00123)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ITGB3 Antibody (OABF00123)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ITGB3 Antibody (OABF00123)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ITGB3 Antibody (OABF00123)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "ITGB3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ITGB3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ITGB3"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ITGB3"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ITGB3"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ITGB3"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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