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Datasheets/Manuals | Printable datasheet for ITGAE Antibody (OAEE00044) (OAEE00044) |
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Predicted Species Reactivity | Human|Non-human Primate |
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Product Format | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
Clonality | Monoclonal |
Clone | Ber-ACT8 |
Isotype | IgG1 |
Host | Mouse |
Application | Flow cytometry|Immunohistochemistry-Frozen|Immunoprecipitation|Western blot |
Reconstitution and Storage | 2°C to 8°C |
Immunogen | HTLV-1 induced human T cell line MAPS16 |
Purification | Purified |
Concentration | 1 mg/ml |
Specificity | The mouse monoclonal antibody Ber-ACT8 recognizes CD103 (alpha E integrin), a type I transmembrane glycoprotein primarily found on intestinal intraepithelial lymphocytes. HLDA V; WS Code A067 |
Formulation | Purified |
Purity | > 95% (by SDS-PAGE) |
Storage Buffer | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
Reference | Poles MA, Barsoum S, Yu W, Yu J, Sun P, Daly J, He T, Mehandru S, Talal A, Markowitz M, Hurley A, Ho D, Zhang L: Human immunodeficiency virus type 1 induces persistent changes in mucosal and blood gammadelta T cells despite suppressive therapy. J Virol. 2003 Oct;77(19):10456-67. León F, Roy G: Isolation of human small bowel intraepithelial lymphocytes by annexin V-coated magnetic beads. Lab Invest. 2004 Jun;84(6):804-9. Sigmundsdottir H, Johnston A, Gudjonsson JE, Bjarnason B, Valdimarsson H: Methotrexate markedly reduces the expression of vascular E-selectin, cutaneouslymphocyte-associated antigen and the numbers of mononuclear leucocytes in psoriatic skin. Exp Dermatol. 2004 Jul;13(7):426-34. Kost CB, Holden JT, Mann KP: Marginal zone B-cell lymphoma: a retrospective immunophenotypic analysis. Cytometry B Clin Cytom. 2008 Sep;74(5):282-6. Kost CB, Holden JT, Mann KP: Marginal zone B-cell lymphoma: a retrospective immunophenotypic analysis. Cytometry B Clin Cytom. 2008 Sep;74(5):282-6. Brandes M, Willimann K, Lang AB, Nam KH, Jin C, Brenner MB, Morita CT, Moser B: Flexible migration program regulates gamma delta T-cell involvement in humoral immunity. Blood. 2003 Nov 15;102(10):3693-701. French JJ, Cresswell J, Wong WK, Seymour K, Charnley RM, Kirby JA: T cell adhesion and cytolysis of pancreatic cancer cells: a role for E-cadherin in immunotherapy? Br J Cancer. 2002 Oct 21;87(9):1034-41. Cardoso CR, Garlet GP, Moreira AP, Júnior WM, Rossi MA, Silva JS: Characterization of CD4+CD25+ natural regulatory T cells in the inflammatory infiltrate of human chronic periodontitis. J Leukoc Biol. 2008 Jul;84(1):311-8. Zhang L, Bertucci AM, Ramsey-Goldman R, Burt RK, Datta SK: Regulatory T cell (Treg) subsets return in patients with refractory lupus following stem cell transplantation, and TGF-beta-producing CD8+ Treg cells are associated with immunological remission of lupus. J Immunol. 2009 Nov 15;183(10):6346-58. Jaensson E, Uronen-Hansson H, Pabst O, Eksteen B, Tian J, Coombes JL, Berg PL, Davidsson T, Powrie F, Johansson-Lindbom B, Agace WW: Small intestinal CD103+ dendritic cells display unique functional properties that are conserved between mice and humans. J Exp Med. 2008 Sep 1;205(9):2139-49. |
Gene Symbol | ITGAE |
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Gene Full Name | integrin subunit alpha E |
Alias Symbols | antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide;CD103;HML-1 antigen;human mucosal lymphocyte antigen 1, alpha polypeptide;HUMINAE;integrin alpha-E;integrin alpha-IEL;integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide);mucosal lymphocyte 1 antigen. |
NCBI Gene Id | 3682 |
Protein Name | Integrin alpha-E |
Description of Target | Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. |
Uniprot ID | P38570 |
Protein Accession # | NP_002199.3 |
Nucleotide Accession # | NM_002208.4 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "ITGAE Antibody (OAEE00044)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Non-human Primate".
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How long will it take to receive "ITGAE Antibody (OAEE00044)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "ITGAE Antibody (OAEE00044)" provided in?
This item is provided in "Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "ITGAE Antibody (OAEE00044)"?
This target may also be called "antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide;CD103;HML-1 antigen;human mucosal lymphocyte antigen 1, alpha polypeptide;HUMINAE;integrin alpha-E;integrin alpha-IEL;integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide);mucosal lymphocyte 1 antigen." in publications.
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What is the shipping cost for "ITGAE Antibody (OAEE00044)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "ITGAE Antibody (OAEE00044)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "ITGAE Antibody (OAEE00044)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "ITGAE Antibody (OAEE00044)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "ITGAE"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "ITGAE"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "ITGAE"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "ITGAE"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "ITGAE"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "ITGAE"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.