ITGA4 Antibody : PE (OATA00335)

Catalog No: OATA00335

Human peripheral blood lymphocytes were stained with 5 uL (0.25 ug) PE Anti-Human CD49d (OATA00335) (solid line) or 0.25 ug PE Mouse IgG1 isotype control (dashed line).

Product Info

• Tested Species Reactivity: Human
• Product Format: Liquid. 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2
• Clonality: Monoclonal
• Clone: 9F10
• Isotype: Mouse IgG1, kappa
• Host: Mouse
• Conjugation: PE: Phycoerythrin
• Application: FC
  Excitation Laser: Blue (488 nm), Green (532 nm), Yellow-Green (561 nm)
  Emmision: 578 nm
• Reconstitution and Storage: 2-8C protected from light
• Specificity: CD49d
• Application Info: This antibody preparation has been pre-titrated and quality-tested for flow cytometry using an appropriate cell type. The antibody has been diluted for use at 5 uL per test, defined as the amount of antibody that will stain a cell sample in a final volume of approximately 100 uL. The number of cells within a sample should be determined empirically, but typically ranges between 1x10e5 to 1x10e8 cells.

Target Info

• Gene Symbol: ITGA4
• Gene Full Name: integrin subunit alpha 4
• Alias Symbols: IA4, CD49D
• NCBI Gene Id: 3676
• Protein Name: integrin alpha-4
• Description of Target: The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants.
• Uniprot ID: P13612
• Protein Accession #: NP_000876.3
• Nucleotide Accession #: NM_000885.5