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Conjugation Options

ARP40392_T100-FITC Conjugated

ARP40392_T100-HRP Conjugated

ARP40392_T100-Biotin Conjugated

ISG20 Antibody - N-terminal region (ARP40392_T100)

Catalog#: ARP40392_T100
Domestic: within 1-2 days delivery International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-34109 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human ISG20
Purification Protein A purified
Predicted Homology Based on Immunogen Sequence Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 79%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 93%; Rat: 93%
Complete computational species homology data Anti-ISG20 (ARP40392_T100)
Peptide Sequence Synthetic peptide located within the following region: GAVLYDKFIRPEGEITDYRTRVSGVTPQHMVGATPFAVARLEILQLLKGK
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-ISG20 (ARP40392_T100) antibody is Catalog # AAP40392 (Previous Catalog # AAPP22136)
Datasheets/Manuals Printable datasheet for anti-ISG20 (ARP40392_T100) antibody
Sample Type Confirmation

ISG20 is strongly supported by BioGPS gene expression data to be expressed in Daudi

Target Reference Horio,T., FEBS Lett. 577 (1-2), 111-116 (2004)

Zahoor, M. A. et al. HIV-1 Vpr Induces Interferon-Stimulated Genes in Human Monocyte-Derived Macrophages. PLoS One 9, e106418 (2014). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat 25170834

Gene Symbol ISG20
Official Gene Full Name Interferon stimulated exonuclease gene 20kDa
Alias Symbols CD25, HEM45
NCBI Gene Id 3669
Protein Name Interferon-stimulated gene 20 kDa protein
Description of Target ISG20 belongs to the the exonuclease superfamily. It is exonuclease with specificity for single-stranded RNA and, to a lesser extent for DNA. It degrades RNA at a rate that is approximately 35-fold higher than its rate for single-stranded DNA. It is involved in the antiviral function of IFN against RNA viruses.
Swissprot Id Q96AZ6
Protein Accession # NP_002192
Nucleotide Accession # NM_002201
Protein Size (# AA) 181
Molecular Weight 20kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express ISG20.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express ISG20.
Protein Interactions UBC;
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