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ISG15 (9A1) Mouse mAb (OAAH00023)

100 ul
$220.00
In Stock
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Gene Symbol:
ISG15
NCBI Gene Id:
9636
Protein Name:
Ubiquitin-like protein ISG15
Swissprot Id:
P05161
Alias Symbols:
G1P2, IP17, UCRP, IFI15, hUCRP,
Replacement Item:
This antibody may replace item sc-130791 from Santa Cruz Biotechnology.
Description of Target:
ISG15 (Interferon Stimulating Gene 15, also known as Ubiquitin Cross-reactive Protein (UCRP) is an 15 kDa ubiquitin-like protein containing two ubiquitin homology domains. ISC15 is induced to express in response to IFN alpha or IFN beta, but not IFN gamma. ISG15 post-translationally modifies proteins via a pathway parallel to, and partially overlapping with, that of ubiquitin. In addition, ISG15 is released from cells to mediate extracellular cytokine-like activities. Its modification system plays important roles in the innate immune response, regulation of interferon signaling, pregnancy, and several cancers.
Molecular Weight:
15 kDa
Host:
Mouse
Clonality:
Monoclonal
Application:
SDS-PAGE, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express ISG15.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express ISG15.
Immunogen:
This Aviva monoclonal antibody is produced by immunizing mice with humanISG15 full-length protein.
Predicted Species Reactivity:
Human
Reconstitution and Storage:
Store the product at -20C. Stable for one year from the date of shipment.
Datasheets/Manuals:
Printable datasheet for ISG15 (9A1) Mouse mAb (OAAH00023) OAAH00023
Specificity:
ISG15 (9A1) Mouse mAb detects endogenous level of total ISG15 protein.
Source:
Mouse mAb
Isotype:
Mouse IgG
Application Info:
WB: 1:1000
Target Reference:
1. Blomstrom DC, Fahey D, Kutny R, Korant BD, Knight Jr E. Molecular
characterization of the interferon-induced 15-kDa protein. Molecular cloning
and nucleotide and amino acid sequence. J Biol Chem 1986;261:8811–6.
2. Au WC, Moore PA, Lowther W, Juang YT, Pitha PM. Identification of a
member of the interferon regulatory factor family that binds to the
interferon-stimulated response element and activates expression of
interferon-induced genes. Proc Natl Acad Sci USA 1995;92:11657–61.

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