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IRS-1 Antibody (Phospho-Ser1101) (OAEC01912)

100ug
$229.00
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Conjugation Options

OAEC01912-FITC Conjugated

OAEC01912-HRP Conjugated

OAEC01912-Biotin Conjugated

Predicted Species Reactivity:
Human, Mouse, Rat
Product Format:
Liquid
Clonality:
Polyclonal
Host:
Rabbit
Application:
WB, IHC
Additional Information:
All site: Human: Ser1101; Mouse: Ser1097; Rat: Ser1100
Reconstitution and Storage:
Store at -20C/1 year
Replacement Item:
This antibody may replace item sc-177402 from Santa Cruz Biotechnology.
Immunogen:
The antiserum was produced against synthesized phosphopeptide derived from humanIRS-1 around the phosphorylation site of serine 1101 (H-S-SP -E-T).
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation
Concentration:
1 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-IRS1 antibody OAEC01912
Specificity:
IRS-1 (Phospho-Ser1101) antibody detects endogenous levels of IRS-1 only whenphosphorylated at serine 1101.
Formulation:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application Info:
WB: 1:500-1:1000, IHC: 1:50-1:100, ELISA: 1:5000
Target Reference:
XJ Sun, J. Biol. Chem., Nov 1992; 267: 22662 - 22672.Laurent Delahaye, Endocrinology, Dec 1998; 139: 4911.Angela M. Valverde, Mol. Cell. Biol., Apr 2001; 21: 2269 - 2280. Xiao Jian Sun, J. Biol. Chem., May 1996; 271: 10583.
Gene Symbol:
IRS1
Official Gene Full Name:
Insulin receptor substrate 1
NCBI Gene Id:
3667
Protein Name:
Insulin receptor substrate 1
Swissprot Id:
P35568
Protein Accession #:
NP_005535.1
Molecular Weight:
132 kDa
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express IRS1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express IRS1.

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