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IRF6 Antibody (OAEB01781)

100 ug
In Stock
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Gene Symbol:
NCBI Gene Id:
Protein Name:
Interferon regulatory factor 6
Swissprot Id:
Protein Accession #:
Alias Symbols:
IRF6, interferon regulatory factor 6, LPS, PIT, PPS, VWS, OFC6
Replacement Item:
This antibody may replace item sc-130790 from Santa Cruz Biotechnology.
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express IRF6.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express IRF6.
Predicted Species Reactivity:
Dog, Horse, Human, Mouse, Pig, Rat, Sheep
Predicted Homology Based on Immunogen Sequence:
Dog: 84%; Horse: 92%; Human: 100%; Mouse: 83%; Pig: 84%; Rat: 91%; Sheep: 83%
Complete computational species homology data:
IRF6 Antibody (OAEB01781)
Peptide Sequence:
Product Format:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Reconstitution and Storage:
Aliquot and store at -20C. Minimize freezing and thawing.
Printable datasheet for anti-IRF6 antibody - OAEB01781
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Application Info:
Peptide ELISA: antibody detection limit dilution 1:32000.
Western Blot: Approx 60kDa band observed in Human Ovary lysates (calculated MW of 53.1kDa according to NP_006138.1). In transfected HEK293 transiently expressing IRF6 a band of approx. 55kDa is observed. This band is not observed in the non-transfected HEK293. Recommended for use at 0.2-0.6ug/ml.
Immunohistochemistry: In paraffin embedded Human Kidney shows strong nuclear staining in DCT and glomerulus. Recommended concentration, 2-3ug/ml.
Target Reference:
* Kondo S, Schutte BC, Richardson RJ, Bjork BC, Knight AS, Watanabe Y, Howard E, de Lima RL, Daack-Hirsch S, Sander A, McDonald-McGinn DM, Zackai EH, Lammer EJ, Aylsworth AS, Ardinger HH, Lidral AC, Pober BR, Moreno L, Arcos-Burgos M, Valencia C, Houdayer C, Bahuau M, Moretti-Ferreira D, Richieri-Costa A, Dixon MJ, Murray JC.; Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes.; Nat Genet. 2002 Oct;32(2):285-9. Epub 2002 Sep 03.; Pubmed 12219090

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