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IRF3 Antibody (OAAF00779)

100 ug
$379.00
In Stock
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Conjugation Options

OAAF00779-FITC Conjugated

OAAF00779-HRP Conjugated

OAAF00779-Biotin Conjugated

Predicted Species Reactivity:
Human, Mouse, Rat
Product Format:
Liquid. PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality:
Polyclonal
Host:
Rabbit
Application:
WB, IHC, IF, ELISA
Reconstitution and Storage:
Stable at -20C for at least 1 year.
Gene Symbol:
IRF3
Official Gene Full Name:
Interferon regulatory factor 3
NCBI Gene Id:
3661
Protein Name:
Interferon regulatory factor 3
Swissprot Id:
Q14653
Protein Accession #:
NP_001184053.1
Replacement Item:
This antibody may replace item sc-15991 from Santa Cruz Biotechnology.
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express IRF3.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express IRF3.
Immunogen:
The antiserum was produced against synthesized peptide derived between 351-400 amino acids from the C-Terminal region of human IRF3.
Datasheets/Manuals:
Printable datasheet for OAAF00779
Specificity:
IRF-3 (Ab-385) antibody detects endogenous levels of total IRF-3 protein
Application Info:
WB 1:500~1:1000
IHC 1:50~1:100
IF 1:100~1:500
ELISA 1:5000
Target Reference:
Wen-Shuz Yeow, J. Virol., Mar 2001; 75: 3021 - 3027.
Subhra K. Biswas, Blood, Mar 2006; 107: 2112 - 2122.
Benjamin R. tenOever, J. Virol., Apr 2002; 76: 3659 - 3669
Publications:

Dong, X.-Y. et al. Classical swine fever virus triggers RIG-I and MDA5-dependent signaling pathway to IRF-3 and NF-κB activation to promote secretion of interferon and inflammatory cytokines in porcine alveolar macrophages. Virol. J. 10, 286 (2013). WB, IHC, IF, ELISA, Human, Mouse, Rat 24034559

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