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Catalog No: OPPA01346 (Formerly GWB-15863F)
Size:10UG
Price: $75.00
SKU
OPPA01346
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IPP-POZ Protein (OPPA01346)

Datasheets/ManualsPrintable datasheet for OPPA01346
Product Info
Predicted Species ReactivityHuman
Product FormatThe protein (1mg/ml) containing 10mM HEPES (pH7.4) and 25mM NaCl. Physical appearance: Sterile filtered colorless solution.
HostE. Coli
::Product Introduction: Intracisternal A particle-promoted polypeptide (IPP) is a 66kDa protein (584 amino acids), which contains an N-terminal POZ protein-protein interaction domain and a C-terminal kelch repeat domain consisting of six tandem arranged repeats. The POZ domain (also called BTB domain) is present near the N-terminus of a fraction of zinc finger proteins and in protein that contain the pfam01344 motif such as kelch and pox virus proteins. The BTB/POZ domain mediates homomeric dimerization and in some instances heteromeric dimerization. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-coR and SMRT.
Product Description: IPP-POZ Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 157 amino acids & having a molecular mass of 17.3 kDa.
Reconstitution and StorageStore at 4C if entire vial will be used within 2-4 weeks. Store, frozen at -20C for longer periods of time. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Avoid multiple freeze-thaw cycles.
PurityGreater than 95.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Peptide SequenceMANEDCPKAA DSPFSSDKHA QLILAQINKM RNGQHFCDVQ LQVGQESFKA HRLVLAASSPYFAALFTGGM KESSKDVVPI LGIEAGIFQI LLDFIYTGIV NIGVNNVQEL IIAADMLQLTEVVHLCCEFL KGQIDPLNCI GIFQFSEQIA CHDLLEF.
Gene SymbolIPP-POZ
Alias SymbolsKLHL27
NCBI Gene Id3652
Protein NameActin-binding protein IPP
Description of TargetRecombinant Human IPP-POZ
Uniprot IDQ9Y573
Protein Accession #NP_005888.1
Protein Size (# AA)Recombinant
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