Size:100 ug
$255.00
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SKU
OAAD00166
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INVOLUCRIN Antibody (OAAD00166)

Catalog#: OAAD00166
Domestic: within 1 week delivery | International: 1 week
More Information
Predicted Species Reactivity Human, dog, Pig
Clonality Monoclonal
Clone IL-9
Isotype IgG1
Host Mouse
Application WB, IHC, IP, ICC
Reconstitution and Storage At -20C for one year. After reconstitution, at 4C for one month. It can also be aliquotted and stored frozen at -20C for longer time.
Replacement Item This antibody may replace item sc-15223 from Santa Cruz Biotechnology.
Immunogen Human involucrin
Purification Purified by the goat anti-mouse IgG Affinity chromatography.
Datasheets/Manuals Printable datasheet for INVOLUCRIN Antibody (OAAD00166) - OAAD00166
Specificity Human, dog, pig.
No cross reactivity with other proteins.
Formulation Lyophilized from 1.2% sodium acetate, with 2mg BSA and 0.01mg NaN3 as preservative.
Application Info Western blot At 2ug/ml with the appropriate system to detect involucrin in cells and tissues.
Immunohistochemistry(P) At 0.4-1ug/ml to detect involucrin in formalin fixed and paraffin embedded tissues.
Immunohistochemistry(F) At 0.4-1ug/ml to detect involucrin in formalin or acetone fixed tissues.
Immunocytochemistry Suitable Other applications have not been tested.
Optimal dilutions should be determined by end user.
Storage Buffer 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.
Target Reference 1. Eckert, R. L.; Green, H. : Structure and evolution of the human involucrin gene. Cell 46: 583-589, 1986.
2. Djian, P.; Delhomme, B.; Green, H. : Origin of the polymorphism of the involucrin gene in Asians. Am.
J. Hum. Genet. 56: 1367-1372, 1995.
3. Djian, P.; Delhomme, B.; Green, H. : Origin of the polymorphism of the involucrin gene in Asians. Am.
J. Hum. Genet. 56: 1367-1372, 1995.
Gene Symbol IVL
NCBI Gene Id 3713
Protein Name Involucrin
Description of Target Involucrin is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. The gene consists of 585 amino acids, 390 of which form a central decapeptide repeat, rich in glutamine and glutamic acid. The involucrin gene, encoding a protein of the terminally differentiated keratinocyte, is polymorphic in the human. Involucrin has previously been mapped to chromosome 1q21. The epidermal protein involucrin has been remodeled in the higher primates. And the existence of two populations of East Asian involucrin alleles gives support for the existence of a Eurasian stem lineage from which Caucasians and a part of the Asian population originated.
Swissprot Id P07476
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express IVL.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express IVL.
  1. What is the species homology for "INVOLUCRIN Antibody (OAAD00166)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, dog, Pig".

  2. How long will it take to receive "INVOLUCRIN Antibody (OAAD00166)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "INVOLUCRIN Antibody (OAAD00166)" provided in?

    This item is provided in "".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "INVOLUCRIN Antibody (OAAD00166)"?

    This target may also be called "" in publications.

  5. What is the shipping cost for "INVOLUCRIN Antibody (OAAD00166)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "INVOLUCRIN Antibody (OAAD00166)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "INVOLUCRIN Antibody (OAAD00166)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "INVOLUCRIN Antibody (OAAD00166)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "IVL"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "IVL"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "IVL"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "IVL"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "IVL"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "IVL"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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