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Catalog No: OOMC00057
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OOMC00057
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Datasheets/ManualsPrintable datasheet for OOMC00057
Product Info
Product FormatPowder
Additional InformationCAS: 1224844-38-5
Molecular Formula: C15H15N7O
::Chemical Name: 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
::Primary Activity: mTOR and PI3K inhibitor, Autophagy modulator
::COVID-19 Rationale: mTORC1 pathway members interact with SARS-CoV-2 N and Orf8 proteins
Reconstitution and StorageSoluble in DMSO (up to 25 mg/ml). Store at -20C.
Purity> 98%
Reference 1) Hsieh et al. (2012), The translational landscape of mTOR signaling steers cancer initiation and metastasis; Nature, 485 55 2) Gokmen-Polar et al. (2012) Investigational drug MLN0128, a novel TORC1/2 inhibitor, demonstrates potent oral antitumor activity in human breast cancer xenograft models; Breast Cancer Res. Treat., 136 673
Alias SymbolsMLN-0128
Molecular Weight309.33 g/mol
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