Catalog No: OOMC00057
Price: $0.00
SKU
OOMC00057
Availability: Domestic: within 1-2 weeks delivery | International: 1-2 weeks
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Shipping Info:
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
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Datasheets/Manuals | Printable datasheet for OOMC00057 |
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Product Format | Powder |
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Additional Information | CAS: 1224844-38-5 Molecular Formula: C15H15N7O |
:: | Chemical Name: 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
:: | Primary Activity: mTOR and PI3K inhibitor, Autophagy modulator |
:: | COVID-19 Rationale: mTORC1 pathway members interact with SARS-CoV-2 N and Orf8 proteins |
Reconstitution and Storage | Soluble in DMSO (up to 25 mg/ml). Store at -20C. |
Purity | > 98% |
Reference | 1) Hsieh et al. (2012), The translational landscape of mTOR signaling steers cancer initiation and metastasis; Nature, 485 55 2) Gokmen-Polar et al. (2012) Investigational drug MLN0128, a novel TORC1/2 inhibitor, demonstrates potent oral antitumor activity in human breast cancer xenograft models; Breast Cancer Res. Treat., 136 673 |
Alias Symbols | MLN-0128 |
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Molecular Weight | 309.33 g/mol |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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