INHA Antibody (OAEC04316)

Catalog No: OAEC04316

Size:100 ug/100 ul

Immunohistochemical analysis of paraffin-embedded human lymphoid (A), ovary tumor (B) and testicle tumor (C) tissues using INHA mouse mAb with DAB staining.

Confocal immunofluorescence analysis of Hela cells using INHA mouse mAb (green). Red. Actin filaments have been labeled with DY-554 phalloidin. Blue. DRAQ5 fluorescent DNA dye.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Purified antibody in PBS containing 0.03% sodium azide
• Clonality: Monoclonal
• Clone: 4A2
• Isotype: IgG1
• Host: Mouse
• Application: IF, IHC
• Reconstitution and Storage: Store at 4C, for long term storage, store at -20C.
• Immunogen: Purified recombinant fragment of human INHA expressed in EColi.
• Concentration: 1 mg/ml
• Application Info: IF: 1/200 - 1/1000
  IHC: 1/200 - 1/1000
  ELISA: 1/10000
  Figure 1 Immunohistochemical analysis of paraffin-embedded human lym phoid (A)
  ovary tumor (B) and testicle tumor (C) tissues using INHA mouse mAb with DAB staining
  

Target Info

• Gene Symbol: INHA
• Gene Full Name: inhibin, alpha
• NCBI Gene Id: 3623
• Description of Target: INHA (A-inhibin subunit precursor, inhibin alpha subunit ), also called inhibin (alpha) , which is located on chromosome 2q33-q36. Inhibin is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises of two subunits, Inhibin A and B. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tum or suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa cell tum ors and can therefore be used as a marker for primary as well as recurrent disease. In addition to their role in endocrine feedback in the reproductive sytem, inhibins subserve local regulatory roles in numerous extragonadal tissues, including brain, adrenal, bone marrow, placenta, and most notably anterior pituitary. Inhibin alpha subunit gene expres sion is down regulated in human prostate cancer, suggesting a tum or suppressive role.
• Uniprot ID: P05111
• Molecular Weight: 40 kDa