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ING4 Antibody - middle region (ARP50608_P050)

100 ul
$289.00
In Stock
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Conjugation Options

ARP50608_P050-FITC Conjugated

ARP50608_P050-HRP Conjugated

ARP50608_P050-Biotin Conjugated

Tested Species Reactivity:
Human
Predicted Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality:
Polyclonal
Host:
Rabbit
Application:
WB
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Gene Symbol:
ING4
Official Gene Full Name:
Inhibitor of growth family, member 4
NCBI Gene Id:
51147
Protein Name:
Inhibitor of growth protein 4
Swissprot Id:
Q9UNL4
Protein Accession #:
NP_057246
Nucleotide Accession #:
NM_016162
Alias Symbols:
MGC12557, my036, p29ING4
Replacement Item:
This antibody may replace item sc-121066 from Santa Cruz Biotechnology.
Description of Target:
ING4 is a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway.This gene encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins.
Protein Size (# AA):
248
Molecular Weight:
28kDa
Purification:
Affinity Purified
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express ING4.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express ING4.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human ING4
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 87%; Guinea Pig: 87%; Horse: 87%; Human: 100%; Mouse: 100%; Rabbit: 87%; Rat: 87%
Complete computational species homology data:
Anti-ING4 (ARP50608_P050)
Peptide Sequence:
Synthetic peptide located within the following region: DLKEKQIESSDYDSSSSKGKKSRTQKEKKAARARSKGKNSDEEAPKTAQK
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
NAV2; GADD45A; SUV39H1; RELA; CDC34; HIST3H3; MSX1; TP53; PADI4; ING4; KAT7; JADE1; UBC; HIST1H3A; TLX3; JADE2; HOXB9; Trp53; EGLN1; G3BP2; PPFIA1; UBE2D2; EP300; HHT2; HHT1; HIST2H3C; JADE3; MEAF6; CDKN2A;
Blocking Peptide:
For anti-ING4 (ARP50608_P050) antibody is Catalog # AAP50608 (Previous Catalog # AAPS26506)
Datasheets/Manuals:
Printable datasheet for anti-ING4 (ARP50608_P050) antibody
Sample Type Confirmation:

ING4 is supported by BioGPS gene expression data to be expressed in HEK293T

Target Reference:
Li,X., (2008) Anat Rec (Hoboken) 291 (5), 593-600

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