Catalog No: ARP54363_P050
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ARP54363_P050
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Datasheets/ManualsPrintable datasheet for anti-IMPDH1 (ARP54363_P050) antibody
Product Info
ReferenceWang,J., (2008) Clin. Pharmacol. Ther. 83 (5), 711-717
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationIHC, WB
Additional InformationIHC Information: Human Pancreas (formalin-fixed, paraffin-embedded) stained with IMPDH1 antibody ARP54363_P050 followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
IHC Information: Human Pancreas (formalin-fixed, paraffin-embedded) stained with IMPDH1 antibody ARP54363_P050 followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human IMPDH1
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 79%; Zebrafish: 100%
Peptide SequenceSynthetic peptide located within the following region: KKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTRE
Concentration0.5 mg/ml
Blocking PeptideFor anti-IMPDH1 (ARP54363_P050) antibody is Catalog # AAP54363 (Previous Catalog # AAPP31138)
Sample Type Confirmation

IMPDH1 is supported by BioGPS gene expression data to be expressed in HeLa

Enhanced Validation
Relative Expression (Western Blot) Avivasheild
Gene SymbolIMPDH1
Gene Full NameIMP (inosine 5'-monophosphate) dehydrogenase 1
Alias SymbolsIMPD, RP10, IMPD1, LCA11, IMPDH-I, sWSS2608
NCBI Gene Id3614
Protein NameInosine-5'-monophosphate dehydrogenase 1
Description of TargetIMPDH1 acts as a homotetramer to regulate cell growth. It is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10).
Uniprot IDP20839
Protein Accession #NP_899066
Nucleotide Accession #NM_183243
Protein Size (# AA)514
Molecular Weight55 kDa
Protein InteractionsUBC; LAMP2; IMPDH2; XRCC6; GMNN; HTRA1; DDX3X; SUMO4;
  1. What is the species homology for "IMPDH1 Antibody - middle region (ARP54363_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish".

  2. How long will it take to receive "IMPDH1 Antibody - middle region (ARP54363_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "IMPDH1 Antibody - middle region (ARP54363_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "IMPDH1 Antibody - middle region (ARP54363_P050)"?

    This target may also be called "IMPD, RP10, IMPD1, LCA11, IMPDH-I, sWSS2608" in publications.

  5. What is the shipping cost for "IMPDH1 Antibody - middle region (ARP54363_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "IMPDH1 Antibody - middle region (ARP54363_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "IMPDH1 Antibody - middle region (ARP54363_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "55 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "IMPDH1 Antibody - middle region (ARP54363_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "IMPDH1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "IMPDH1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "IMPDH1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "IMPDH1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "IMPDH1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "IMPDH1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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