ILK Antibody - C-terminal region (ARP30445_P050)

Catalog No: ARP30445_P050

Host: Rabbit
Target Name: ILK
Sample Type: Jurkat Whole Cell lysates
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target Name: ILK
Sample Tissue: Mouse Testis
Antibody Dilution: 1ug/ml

Host: Mouse
Target Name: ILK
Sample Tissue: Mouse Testis
Antibody Dilution: 1ug/ml

Product Info

• Tested Species Reactivity: Human, Mouse
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ILK
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Goat: 82%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%
• Peptide Sequence: Synthetic peptide located within the following region: MKVALEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIVPILEKMQD
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-ILK (ARP30445_P050) antibody is Catalog # AAP30445

Target Info

• Gene Symbol: ILK
• Gene Full Name: integrin-linked kinase
• Alias Symbols: P59, ILK-1, ILK-2, p59ILK, HEL-S-28
• NCBI Gene Id: 3611
• Protein Name: Integrin-linked protein kinase
• Description of Target: Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
• Uniprot ID: Q13418
• Protein Accession #: NP_004508
• Nucleotide Accession #: NM_004517
• Protein Size (# AA): 452
• Molecular Weight: 49kDa
• Protein Interactions: UBC; TRIM27; PARVG; PARVA; RICTOR; ITGB1; MTOR; AKT1; FKBP5; HSPH1; FAF1; CARM1; UGP2; PPAT; FBXO6; ACACA; LIMS2; RHOT1; FANCI; ATAD3A; HEATR1; CLN6; TRAFD1; ZNF568; TIMM50; RHOT2; TRABD; LPCAT1; VKORC1; RPL13; ABCE1; RBBP7; RAF1; SDF4; SEC61A1; PARVB; AK